Difference between revisions of "Nasal Cavity - Degenerative Pathology"

Revision as of 21:33, 4 August 2008

Deposition of amyloid in nasal submucosa of horses
Not part of generalised amyloidosis
May extend to larynx
Nodular of diffuse
Stenosis may cause obstruction
Smooth surface, waxy sheen on cut surface
Macrophages and lymphocytes, giant cells
May have overlying ulceration of mucosa
Large firm nodules in alar folds, rostral nasal septum and floor of nasal cavity
Micro:
- Deposition of hyaline material in nasal mucosa

Congestion - passive interference with venous return
- Non-specific
- Commonly found at post-mortem
Hyperaemia - active vasodilation
- Associated with early stages of inflammation

Can result from local trauma or just transfer blood from lower down in the respiratory tract (see epistaxis)

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+==In Horses==
+===Nasal septum abnormalities===
+*Thickening caused by
+**Trauma
+**Infection
+**[[Nasal Cavity Hyperplastic and Neoplastic - Pathology|Neoplasia of nasal septum]], carcinomas most common
+**Amyloidosis (below)
+**[[Nasal Cavity Developmental - Pathology#Wry nose|Wry nose]]
+**[[Paranasal Sinuses Inflammatory - Pathology|Empyema]], [[Paranasal Sinuses Hyperplastic and Neoplastic - Pathology|neoplasia]], [[Paranasal sinuses - Pathology|cysts]] of sinuses
+===Nasal amyloidosis===
+*Deposition of amyloid in nasal submucosa of horses
+*Not part of generalised amyloidosis
+*May extend to [[Larynx - Anatomy & Physiology|larynx]]
+*Nodular of diffuse
+*Stenosis may cause obstruction
+*Smooth surface, waxy sheen on cut surface
+*Macrophages and lymphocytes, giant cells
+*May have overlying ulceration of mucosa
+*Large firm nodules in alar folds, rostral nasal septum and floor of nasal cavity
+*Micro:
+**Deposition of hyaline material in nasal mucosa
+==Circulatory disturbances==
+===Congestion and Hyperaemia===
+*Congestion - passive interference with venous return
+**Non-specific
+**Commonly found at post-mortem
+*Hyperaemia - active vasodilation
+**Associated with early stages of inflammation
+===Haemorrhage===
+*Can result from local trauma or just transfer blood from lower down in the respiratory tract (see [[Respiratory System Clinical Signs - Pathology#Epistaxis|epistaxis]])