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| | ====Dog==== | | ====Dog==== |
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| − | ====Pig==== | + | ====[[Gastric Ulceration - Pig]]==== |
| − | [[Gastric Ulceration - all species]] | |
| − | * Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses.
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| − | * Has serious economic consequences.
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| − | *'''Clinical'''
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| − | ** Occasionally a well-grown pig will drop dead.
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| − | *** Deep ulcers have eroded into a blood vessel, causing massive haemorrhage into the [[Forestomach - Anatomy & Physiology|stomach]] from and producing death very rapidly.
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| − | ** If long standing ulcers do not result in death, they do produce pain and discomfort.
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| − | *** Give low growth rate and poor feed conversion.
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| − | *'''Pathogenesis'''
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| − | ** Gastric ulceration is associated with modern pig rearing, but the exact cause is unknown.
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| − | ** Causes are associated with gastric hyperacidity, and gastric ulceration is probably a multifactorial disease.
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| − | ** The following are suggested as possible causes:
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| − | *** Infection, e.g. ''Candida albicans'', ''Streptococci'', ''Staphylococci'' and mixes of these.
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| − | *** Copper toxicity- this is probably more significant.
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| − | **** Pigs are fed copper as growth promoter; 50 ppm is know to be toxic, and animals are often fed 250 ppm.
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| − | *** Vitamin E / Selenium deficiency.
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| − | *** Feeding on concrete floors.
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| − | **** Sand is licked up whe pigs eat.
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| − | *** Feeding finely milled cereal.
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| − | *** Stress
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| − | *** Possibly genetic factors.
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| − | *'''Pathology'''
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| − | ** Most commonly affects pars oesophagea (squamous or non-glandular portion).
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| − | ** Starts with hyperkeratosis in the stratum corneum
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| − | *** Appears rough and thickened
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| − | *** May stop at this stage.
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| − | ** In approximately 30% of animals, the lesion starts to erode and quite deep ulcers may develop.
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| − | ** In a significant small number ,very deep ulcers develop and may affect virtually all of pars oesophagea.
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| − | ** Histologically, ulcers are large and flask-shaped ulcer with fibrin, necrosis, erosion and fibrosis at base.
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| | [[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]] | | [[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]] |