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| == [[Portosystemic Shunt]] == | | == [[Portosystemic Shunt]] == |
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− | == Idiopathic noncirrhotic portal hypertension == | + | == [[Portal Hypertension, Idiopathic Noncirrhotic]] == |
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− | JAVMA paper
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− | *Portal hypertension
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− | *Sustained impairment of forward venous flow anywhere along the path from the portal vein to the right side of the heart.
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− | *Luminal (thrombosis, parasites) or extraluminal obstruction (hepatic fibrosis or nodular regeneration) or relative restriction of flow due to massive portal volume overload (arterioportal fistulas).
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− | *Hepatomegaly associated with posthepatic obstruction
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− | *Microhepatica – associated with prehepatic/hepatic causes.
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− | *Hepatic encephalopathy and GI bleeding not associated with posthepatic causes.
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− | *Most common causes are RHS heart failure and severe diffuse hepatobiliary disease that results in cirrhosis.
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− | ===Histology===
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− | *indistinguishable from microvascular dysplasia or surgically created portosystemic shunts
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− | **Portal triad arteriole proliferation
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− | **portal veins small to large
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− | **variable portal triad fibrosis
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− | **hepatic lobule size variation
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− | **arterioles scattered throughout hepatic parenchyma
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− | **portal veins – small
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− | **expanded perivenular connective tissue by arterioles and distended lymphatics.
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| [[Category:Liver_-_Pathology]] | | [[Category:Liver_-_Pathology]] |