Difference between revisions of "Pancreatic Hypoplasia"
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===Microscopic appearance=== | ===Microscopic appearance=== | ||
| − | *Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[ | + | *Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreatic Atrophy, Juvenile|juvenile atrophy]] |
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells | *Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells | ||
[[Category:Pancreas - Developmental Pathology]][[Category:Cattle]][[Category:Cat]][[Category:Dog]] | [[Category:Pancreas - Developmental Pathology]][[Category:Cattle]][[Category:Cat]][[Category:Dog]] | ||
Revision as of 13:11, 9 June 2010
Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine
- Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
- Endocrine part of the pancreas seems unaffected
Clinical signs
- Exocrine Pancreatic Insufficiency
- Occurs at about one year of age
- Onset often preceded by another illness
Gross appearance
- Pot-bellied appearance on external view
- Intestines are distended by bulky fatty ingesta
- Lack of fat in the mesentery and rest of the abdomen
- The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
- The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
Microscopic appearance
- Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the pancreas is normal at birth but undergoes progressive regression - juvenile atrophy
- Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells