IGF-1 - Anatomy & Physiology

Overview

Danielle Keller 2007 Schematic structure of Insulin-like growth factor-1.

IGF-1 is one of a number of Insulin-like growth factors. Insulin-Like Growth Factors are produced by many different tissues and have local paracrine and autocrine effects. (see hormones for further details). They bind to carrier proteins to extend their half life in the blood. The liver is the main source of IGF-1.

Actions of IGF-1

Increased protein synthesis and increased chondrogenesis, both promoting growth.