Liver Flashcards - Pathology

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ALIMENTARY FLASHCARDS



Introduction

  • This Page contains Flashcards for the pathology of the Liver
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Flashcards

Question Answer Article
Liver lesions are common because:
  • it is an area of high metabolic activity
  • receives toxic agents from the gut via the portal blood system
  • has an extensive vascular supply (prime site for metastatic disease)
Link to Answer Article
In each type of jaundice, will bilirubinuria be detected?
  • haemolytic
  • obstructive
  • hepatocellular
  • NO - because most of bilirubin is unconjugated
  • YES - because conjugated bilirubin accumulates
  • NO - because bilirubin fails to conjugate due to liver cell damage
  • NB - the kidney can only excrete the water soluble conjugate
Link to Answer Article
In regards to secondary photosensitisation, what are two hepatotoxic plants?
  • Senecio jacobea (Ragwort)
  • Lantana camara (Lantana)
  • Lupinus angustifolius (Lupins)
  • Blue-green algae
Link to Answer Article
What are two causes of necrosis?
  • severe metabolic disturbances
  • nutritional deficiencies
  • toxic substances
  • actions of micro-organisms
Link to Answer Article
What can cause the liver to appear greenish-blue post mortem?
  • bacteria degrades blood pigment to hydrogen sulfide
Link to Answer Article
True or false?

Cranial displacements of the liver are the most common.

  • false
Link to Answer Article
What occurs during Congestion?
  • The right side of the heart fails to function properly and blood will back up through the veins into the liver.
Link to Answer Article
True or false?

Congenital melanosis in calves and lambs appears as white discoloration of small irregular portions of the liver.

  • false
Link to Answer Article
Hepatic lipidosis or fatty liver syndrome is associated with -
  • dietary factors: obesity and starvation
  • increased demand for energy: pregnancy, lactation, and starvation in physiological states
  • Diabetes mellitus, ketosis, and pregnancy toxaemia in pathological conditions
  • abnormal hepatocytic function: prevents fatty acids from forming complexes with proteins to form low density lipoproteins for secretion into the blood
Link to Answer Article
What could be a non-pathological reason for a cow displaying fatty liver syndrome during necropsy?
  • It is possible to show fat infiltration of liver in cows which have not been eating for several days.
Link to Answer Article
True or false?

Equine hyperlipidemia or fat pony syndrome is similar to that in cats, as well as fatal within a week.

  • true
Link to Answer Article
What causes Lysosomal storage disease and how does it manifest itself?
  • due to an inherited deficiency of lysosomal enzymes
  • manifest themselves as neurological disease
Link to Answer Article
Herpes virus infections include -
  • Equine Viral Rhinopneumonitis
  • Infectious Bovine Rhinotracheitis
  • Feline Viral Rhinopneumonitis
  • Aujesky's disease in pigs
Link to Answer Article
You are examining a cow's liver post-necropsy. You notice the liver has several small areas of necrosis. Is this more likely to be Black Disease or Red Water Disease?
  • Black Disease
Link to Answer Article
What are the two main types of Hepatitis in cats?
  • cholangiohepatitis
  • Lymphocytic portal hepatitis
Link to Answer Article
True or false?

Use of carbon tetrachloride as an anthelmintic and phosphorous as a rodenticide has never been proven to produce liver necrosis.

  • false
Link to Answer Article
Pyrrolizidine alkaloids have an anti-mitotic effect whilst allowing continued synthesis within the cell and its nucleus. This causes a marked increase in the size of parenchymal cells, a phenomenon termed -
  • megalocytosis
Link to Answer Article
What are the two most common primary hepatic neoplasms?
  • liver cell tumours
  • malignant bile duct tumours
Link to Answer Article
Haemangiosarcoma can be primary in the liver, what are other predilection sites?
  • spleen
  • right auricle of the heart
Link to Answer Article
True or false?

Chronic lymphocytic cholangitis generally afflicts only very young cats.

  • false
Link to Answer Article
What are two causes of Cholangitis of the liver?
  • ascending infections from the intestine
  • associated with organisms excreted via the bile
Link to Answer Article