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T cell differentiation (view source)
Revision as of 20:09, 3 September 2008
, 20:09, 3 September 2008→T-Cell Activation
* [[Lymphocytes - WikiBlood#T cells|T cells]] function only after recent activation by antigen.
* [[Lymphocytes - WikiBlood#T cells|T cells]] function only after recent activation by antigen.
* CD4 binds MHC class II.
* CD4 binds MHC class II.
** [[Lymphocytes - WikiBlood#Helper CD4+|CD4+ T-cells]] therefore recognise antigen only in association with MHC class II
** [[Lymphocytes - WikiBlood#Helper CD4+|CD4+ T-cells]] therefore recognise antigen only in association with [[Adaptive Immune System - WikiBlood#Structure and Function of MHC Class I|MHC]] class II
* CD8 binds MHC class I.
* CD8 binds MHC class I.
** [[Lymphocytes - WikiBlood#Cytotoxic CD8+|CD8+ T-cells]] recognise antigen only in association with MHC class I.
** [[Lymphocytes - WikiBlood#Cytotoxic CD8+|CD8+ T-cells]] recognise antigen only in association with [[Adaptive Immune System - WikiBlood#Structure and Function of MHC Class I|MHC]] class I.
* Activation of [[Lymphocytes - WikiBlood#T cells|T cells]] requires two distinct signals.
* Activation of [[Lymphocytes - WikiBlood#T cells|T cells]] requires two distinct signals.
** '''Signal 1'''
** '''Signal 1'''