Frohlich's Adiposogenital Syndrome
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Clinical signs due to a hypothalamic dysfunction.
Decresaed synthesis and release of GnRH means that the pituitary is not stimulated to release FSH or LH at normal levels. Clincally seen as:
- Small, atrophic genitals.
- Feminisation in the male due to lower testosterone release.
Hypothalamus damage also allows incresaed appetite and the animal will be:
- Obese.
- Excess deposition of sub-cut fat.
Compression of local structures also leads to:
- Mental retartdation.
- Diabetes insipidus.
- Visual impairment.