IGF-1 - Anatomy & Physiology

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Insulin-like growth factors

IGF-1 is one of a number of Insulin-like growth factors.

Insulin-Like Growth Factors are produced by many different tissues and have local (paracrine and autocrine - see hormones for further details) effects.

They bind to carrier proteins to extend their half life in the blood.

The Liver is the main source of IGF-1.

Actions of IGF-1

• Increased protein synthesis
• Increased chondrogenesis

• GROWTH