Difference between revisions of "Angiotensin Converting Enzyme"

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Angiotensin converting enzyme is known as '''ACE'''. It is a membrane bound '''metalloproteinase''' and converts Angiotensin 1 to Angiotensin 2.  
 
Angiotensin converting enzyme is known as '''ACE'''. It is a membrane bound '''metalloproteinase''' and converts Angiotensin 1 to Angiotensin 2.  
 +
[[Image:angiotensin.jpg|right|thumb|250px|Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).]]
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It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary ciculation and this is therefore, the site of action of the ACE inhibitor drugs.
 
It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary ciculation and this is therefore, the site of action of the ACE inhibitor drugs.

Revision as of 11:22, 4 January 2011

Overview

Angiotensin converting enzyme is known as ACE. It is a membrane bound metalloproteinase and converts Angiotensin 1 to Angiotensin 2.

File:Angiotensin.jpg
Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).


It is very important in the Renin Angiotensin Aldosterone System (RAAS). ACE is predominantly expressed on epithelial cell membranes in the pulmonary ciculation and this is therefore, the site of action of the ACE inhibitor drugs.