CNS Development - Anatomy & Physiology
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The Central Nervous System's embryological origin is from the neural ectoderm. This is formed as the default pathway from ectoderm to neuroectoderm during development. In the presence of the Lateral Plate Mesoderm (LPM) factor however, ectoderm forms epidermis. To overcome this in development the notochord secretes a LPM factor antagonist allowing the formation of neuroectoderm directly above it. This forms the neural plate and folds to form the neural tube.
- Differentiation of the neural tube at the anterior then forms the brain.
- The diagram on the right shows how the brain transforms during development.
Origins of Functional Types of Neurone
| Nerve | Origin |
|---|---|
| Sensory - Afferent | Neural crest |
| Motor - Efferent | Basal plate of neural tube |
| Association - Interneurones | Alar plate of neural tube |