Difference between revisions of "Epizootic Lymphangitis"

From WikiVet English
Jump to navigation Jump to search
(Created page with '*''Histoplasma capsulatum'' var. ''farciminosum'' **Similar to ''H. capsulatum'' *Occurs in horses, donkeys and mules *90% occurs in horses *Occurs in Europe, Africa and Asia *…')
 
m (Text replace - 'Leukocytes - WikiBlood' to 'Leukocytes')
Line 31: Line 31:
 
**Growth is slow, taking up to 8 weeks
 
**Growth is slow, taking up to 8 weeks
 
**At room temperature, thick-walled chlamydospores can be seen
 
**At room temperature, thick-walled chlamydospores can be seen
**Orgnaisms can usually be seen in swollen [[Leukocytes - WikiBlood|leucocytes]]
+
**Orgnaisms can usually be seen in swollen [[Leukocytes|leucocytes]]
  
 
*Can be stained using Gram, Giemsa, H & E and 10% Methylene Blue followed by Carbol Fuchsin
 
*Can be stained using Gram, Giemsa, H & E and 10% Methylene Blue followed by Carbol Fuchsin

Revision as of 12:50, 12 June 2010

  • Histoplasma capsulatum var. farciminosum
    • Similar to H. capsulatum
  • Occurs in horses, donkeys and mules
  • 90% occurs in horses
  • Occurs in Europe, Africa and Asia
    • Eradicated from the UK but is still under the notifiable Diseases of Animals Act
  • Chronic disease
  • Highly contageous
    • Spread by direct contact or indirect, e.g. through infected grooming equipment, biting flies
  • Once established in a population it is very difficult to eradicate
    • Long incubation peroid
    • New cases can develop weeks or months after the infection appears to have been eradicated
  • Causes ulcerative, nodular lesions
    • Dissemination occurs
    • Pulmonary disease can occur
    • Ulcers rupture, discharging blood-stained pus for several weeks
  • Oval or pear shaped cells
    • Double contoured
    • Dimorphic
      • Grows in the yeast phase at 37°C and in the mycelial phase at room temperature
    • Growth is slow, taking up to 8 weeks
    • At room temperature, thick-walled chlamydospores can be seen
    • Orgnaisms can usually be seen in swollen leucocytes
  • Can be stained using Gram, Giemsa, H & E and 10% Methylene Blue followed by Carbol Fuchsin
  • Enzyme-linked immunosorbant assay can be used to detect the fungi
  • Life-long immunity follows recovery from infection
  • Treatment included potassium iodide, hamycin and Amphotericin B
    • Vaccination has also proven to be effective
    • Injection of hyperimmune serum around skin lesions has been proven to be effective