Difference between revisions of "Gut Endocrine Function - Anatomy & Physiology"
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− | Various regions of the [[Alimentary - Anatomy & Physiology|Alimentary Tract]] secrete [[ | + | Various regions of the [[Alimentary - Anatomy & Physiology|Alimentary Tract]] secrete [[Hormones - Anatomy & Physiology|hormones]] which have various functions within the gastrointestinal tract itself, plus the [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]] and [[Pancreas - Anatomy & Physiology| |
pancreas]]. | pancreas]]. | ||
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|<font color=Purple>Ghrelin</font> | |<font color=Purple>Ghrelin</font> | ||
|[[Forestomach - Anatomy & Physiology|Stomach]] and [[Pancreas - Anatomy & Physiology|Pancreas]] | |[[Forestomach - Anatomy & Physiology|Stomach]] and [[Pancreas - Anatomy & Physiology|Pancreas]] | ||
− | |Increases food intake (by stimulating hunger) at the level of the [[ | + | |Increases food intake (by stimulating hunger) at the level of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]]. |
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|<font color=Purple>Secretin</font> | |<font color=Purple>Secretin</font> |
Revision as of 16:20, 3 September 2008
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Various regions of the Alimentary Tract secrete hormones which have various functions within the gastrointestinal tract itself, plus the liver, gall bladder and pancreas.
Many of the hormones act in a paracrine fashion, exerting their effect on cells close to the secretion site without travelling in the bloodstream.
Hormone | Site of Secretion within GIT | Action |
---|---|---|
Cholecystokinin | Duodenum | Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the pancreas and gall bladder. |
Gastrin | G-Cells in stomach and duodenum | Stimulates Parietal cells in the stomach to secrete HCl and Chief cells to secrete pepsinogen. |
Gastric Inhibitory Peptide | Duodenumand Jejunum | Inhibits gastric motility and HCl secretion in the stomach, induces insulin secretion. |
Ghrelin | Stomach and Pancreas | Increases food intake (by stimulating hunger) at the level of the hypothalamus. |
Secretin | Crypts of Leiberkuhn in the Duodenum | Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release. |
Somatostatin | Gastric glands of the stomach | Inhibits release of gastrin and HCl from the stomach, inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the pancreas. |