• Neutropenia is a reduction in numbers of neutrophils circulating in the blood.



  • Occurs with:
    • Infections caused by Gram-negative organisms.
      • Cause by the effects of their endotoxins.
    • Factors that destroy their formation in the bone marrow.
    • For example
      • Radiation
      • Toxins affecting bone marrow functions
        • E.g. Bracken
      • Some viruses
        • E.g. Parvovirus and Infectious Canine Hepatitis
      • Tumours that replace or displace normal bone marrow.