Difference between revisions of "Pancreas - Anatomy & Physiology - Flashcards"
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− | |<big>'''What | + | |<big>'''What type of gland is the pancreas?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Tubuloalveolar''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Introduction|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''From which embryological germ layer does the pancreas develop from?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Endoderm, except the connective tissue which develops from splanchnic mesoderm''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Development|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''Does the pancreatic duct develop from the dorsal or ventral bud?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Ventral''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Development|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''Where do the ducts of the pancreas open into?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Duodenum; the pancreatic duct opens at the major duodenal papilla with the bile duct; the accessory duct opens at the minor duodenal papilla''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Structure|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What are the | + | |<big>'''What are the functions of the exocrine part of the pancreas?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Produces a secretion that is alkaline to neutralise stomach acid and contains enzymes for digestion''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Exocrine Function|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''Which ions are present withtin the secretion of the pancreas?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Bicarbonate and chloride''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Exocrine Function|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''Why does stomach acid need to be neutralised?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''To provide the optimum pH for pancreatic enzymes, to prevent damage to the thin, absorptive mucosa of the duodenum and to buffer the large intestine''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Exocrine Function|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''Name the cell types present in the islets of Langerhans''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Alpha, beta, delta and F cells''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Endocrine|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What is the antagonist hormone to insulin and what does it do?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Glucagon, it raises blood glucose level''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Endocrine Function|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What is the function of somatostatin?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''It inhibits glucagon and insulin secretion''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Endocrine Function|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What effect does parasympathetic innervation have on glucagon secretion?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Increases it''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What effect does glucagon have on body reserves?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Catabolic''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What is the main target tissue of glucagon?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Liver''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What other tissues does glucagon have an effect on?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Skeletal muscle and adipose tissue''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''Which enzyme does glucagon inactivate in glycolysis?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Pyruvate kinase''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>''' | + | |<big>'''How does glucagon inactivate this enyme?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Phosphorylation via PKA''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What effect does glucagon have on adipose tissue?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Increases β oxidation of fatty acids''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
− | |<big>'''What | + | |<big>'''What effect does glucagon have on skeletal muscle?''' |
||<font color="white"> <big> | ||<font color="white"> <big> | ||
− | *''''' | + | *'''''Increases the rate of protein catabolism''''' |
− | ||[[ | + | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] |
|- | |- | ||
+ | |<big>'''How may ketosis occur during fasting?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''The citric acid cycle turns slowly as oxaloacetate is removed to make glucose. Acetyl CoA builds up and is converted to ketone bodies''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Glucagon|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Describe the structure of insulin.''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''A & B chains linked by disulphide bridges''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Insulin|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Describe the mechanism that causes insulin to be released.''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Glucose enters the β cell through GLUT 2 and is metabolised. ATP depolarises the plasma membrane which leads to calcium signalling causing release of insulin''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Insulin|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''How does insulin enable glucose to be taken up by heptaocytes, adipocytes and skeletal muscle?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''It causes expression of GLUT 4''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Insulin|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''What effect does insulin have on basal metabolic rate?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Increases it in all cells''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Insulin|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''What are the clinical signs of diabetes mellitus?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Glucosuria, polyuria, polydipsia, polyphagia, weight loss, ketosis and ketonuria''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Diabetes Mellitus|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''What are the two causes of diabetes mellitus in dogs?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''β cell deficiency (mainly) and insulin antagonism''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Diabetes Mellitus|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''What are the two types of diabetes in cats?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''IDDM and NIDDM''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Diabetes Mellitus|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''What are the two arteries that supply blood to the pancreas?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Coeliac (left lobe) and cranial mesenteric (right lobe)''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Insulin|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Which hormones increase pancreatic secretion?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''CCK, secretin and gastrin''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Innervation|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Which lymph nodes does lymph from the pancreas drain into?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Pancreatoduodenal''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Lymphatics|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Describe the components of the exocrine pancreas.''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Acini, which consist of 40-50 pyramidal epithelial cells which drain into a lumen''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Histology|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''What is present in the apex of the epithelial cells?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Secretory granules containing the zymogen precursors of the pancreatic enzymes''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Histology|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Which cell type in the islet of Langerhan's produce somatostatin?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''δ cells''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Histology|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Where does the right lobe of the pancreas exits?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Mesoduodenum''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Carnivore|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''In the dog, which of the two ducts of the pancreas is bigger?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Accessory''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Carnivore|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''How many ducts of the pancreas does the cat have?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''One, the pancreatic duct''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Carnivore|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''In which animal group in particular is there a constant secretion of pancreatic juice?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Ruminants''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Ruminants|<span title="Answer article">Link to Answer Article</span>]] | ||
+ | |- | ||
+ | |<big>'''Which shape is the horse's pancreas?''' | ||
+ | ||<font color="white"> <big> | ||
+ | *'''''Triangular''''' | ||
+ | ||[[Pancreas - Anatomy & Physiology#Equine|<span title="Answer article">Link to Answer Article</span>]] | ||
|} | |} | ||
Revision as of 15:03, 26 July 2008
Question | Answer | Article |
---|---|---|
What type of gland is the pancreas? |
|
Link to Answer Article |
From which embryological germ layer does the pancreas develop from? |
|
Link to Answer Article |
Does the pancreatic duct develop from the dorsal or ventral bud? |
|
Link to Answer Article |
Where do the ducts of the pancreas open into? |
|
Link to Answer Article |
What are the functions of the exocrine part of the pancreas? |
|
Link to Answer Article |
Which ions are present withtin the secretion of the pancreas? |
|
Link to Answer Article |
Why does stomach acid need to be neutralised? |
|
Link to Answer Article |
Name the cell types present in the islets of Langerhans |
|
Link to Answer Article |
What is the antagonist hormone to insulin and what does it do? |
|
Link to Answer Article |
What is the function of somatostatin? |
|
Link to Answer Article |
What effect does parasympathetic innervation have on glucagon secretion? |
|
Link to Answer Article |
What effect does glucagon have on body reserves? |
|
Link to Answer Article |
What is the main target tissue of glucagon? |
|
Link to Answer Article |
What other tissues does glucagon have an effect on? |
|
Link to Answer Article |
Which enzyme does glucagon inactivate in glycolysis? |
|
Link to Answer Article |
How does glucagon inactivate this enyme? |
|
Link to Answer Article |
What effect does glucagon have on adipose tissue? |
|
Link to Answer Article |
What effect does glucagon have on skeletal muscle? |
|
Link to Answer Article |
How may ketosis occur during fasting? |
|
Link to Answer Article |
Describe the structure of insulin. |
|
Link to Answer Article |
Describe the mechanism that causes insulin to be released. |
|
Link to Answer Article |
How does insulin enable glucose to be taken up by heptaocytes, adipocytes and skeletal muscle? |
|
Link to Answer Article |
What effect does insulin have on basal metabolic rate? |
|
Link to Answer Article |
What are the clinical signs of diabetes mellitus? |
|
Link to Answer Article |
What are the two causes of diabetes mellitus in dogs? |
|
Link to Answer Article |
What are the two types of diabetes in cats? |
|
Link to Answer Article |
What are the two arteries that supply blood to the pancreas? |
|
Link to Answer Article |
Which hormones increase pancreatic secretion? |
|
Link to Answer Article |
Which lymph nodes does lymph from the pancreas drain into? |
|
Link to Answer Article |
Describe the components of the exocrine pancreas. |
|
Link to Answer Article |
What is present in the apex of the epithelial cells? |
|
Link to Answer Article |
Which cell type in the islet of Langerhan's produce somatostatin? |
|
Link to Answer Article |
Where does the right lobe of the pancreas exits? |
|
Link to Answer Article |
In the dog, which of the two ducts of the pancreas is bigger? |
|
Link to Answer Article |
How many ducts of the pancreas does the cat have? |
|
Link to Answer Article |
In which animal group in particular is there a constant secretion of pancreatic juice? |
|
Link to Answer Article |
Which shape is the horse's pancreas? |
|
Link to Answer Article |