Difference between revisions of "Spermatogenesis and Spermiation - Anatomy & Physiology"

From WikiVet English
Jump to navigation Jump to search
Line 8: Line 8:
 
*Differentiation phase / spermiogenesis - spermatids
 
*Differentiation phase / spermiogenesis - spermatids
  
==The Spermatogenic Cycle==
+
 
 +
[[Image:spermatogenesis.jpg|thumb|right|150px|Spermatogenesis Copyright Amy Cartmel 2008]]
 +
 
 +
==The seminiferous tubule==
 
[[Image:spermatogenesis.jpg|thumb|right|150px|Spermatogenesis Copyright Amy Cartmel 2008]]
 
[[Image:spermatogenesis.jpg|thumb|right|150px|Spermatogenesis Copyright Amy Cartmel 2008]]
  
*Spermatogenesis occurs in the seminipherous tubules of the testes.  
+
The seminiferous tubules are the site of spermatogenesis. The 2 main cell types within the tubules which are involved in spermatogenesis are the germ cells, which will develop into sperm, and somatic cells known as Sertoli cells, which nuture the germ cells throughout the development process.  
*Sertoli cells found within the seminipherous tubules play a vital role in the production of gametes. Sertoli cells are support cells within the seminipherous tubules. They are anchored to the basement membrane and reach all the way to the lumen of the tubules.  The junctional complexes between neighbouring sertoli cells make up the ‘’’blood-testes barrier’’’ which prevents autoimmune reactions against haploid spermatids and spermatozoa by providing an immunologically privileged site. The blood-testes barrier splits the seminipherous epithelium into two main sections; the basal compartment where spermatogonia develop and the adluminal compartment where spermatocytes, spermatids and spermatozoa develop.
+
 
*Spermatogenesis occurs in three phases:
+
As the germ cells progress through their stages of development they move slowly from the basement membrane of the tubules through the tight junction of the Sertoli cells into the tubular lumen.
**'''Proliferation''' - Spermatogonia undergo many mitotic divisions in order to maintain the spermatogonia population in order for spermatogenesis to be continuously producing sperm.
+
 
**'''Meiosis''' -
+
==The proliferation phase==
**'''Differentiation''' -
+
 
 +
The spermatogonia go through several divisions
  
 
==Hormonal Control of Spermatogenesis==
 
==Hormonal Control of Spermatogenesis==

Revision as of 12:50, 28 April 2012


Introduction

Unlike the female production of gametes which occurs entirely before birth with gamete maturation occurring in a pulsatile fashion after puberty, male individuals produce gametes continuously from puberty onwards for the rest of their reproductive lives and the release of the gametes is constant. Spermatogenesis is the process of the gradual transformation of germ cells into spermatozoa. It occurs mainly within the seminiferous tubules of the testes and can be divided into three phases, each of which is associated with different germ cell types:

  • Proliferative phase - spermatogonia
  • Meiotic phase - spermatocytes
  • Differentiation phase / spermiogenesis - spermatids


Spermatogenesis Copyright Amy Cartmel 2008

The seminiferous tubule

Spermatogenesis Copyright Amy Cartmel 2008

The seminiferous tubules are the site of spermatogenesis. The 2 main cell types within the tubules which are involved in spermatogenesis are the germ cells, which will develop into sperm, and somatic cells known as Sertoli cells, which nuture the germ cells throughout the development process.

As the germ cells progress through their stages of development they move slowly from the basement membrane of the tubules through the tight junction of the Sertoli cells into the tubular lumen.

The proliferation phase

The spermatogonia go through several divisions

Hormonal Control of Spermatogenesis

The production of sperm is controlled by hormones influencing sertoli cells rather than sperm cells directly. Hormonal control is via the two gonadotrophins luteinising hormone (LH) and follicle-stimulating hormone (FSH).

  • LH acts on the interstitial leydig cells stimulating them to produce the androgen testosterone.
  • FSH acts on the sertoli cells within the seminipherous tubules stimulating production of Androgen Binding Protein as well as Inhibin



Spermatogenesis and Spermiation - Anatomy & Physiology Learning Resources
VideoWikiVideo.png
Videos
Selection of relevant videos
Dissection of the equine testicle
Category:Histology PowerPointsPowerPoint.png
PowerPoint
Selection of relevant PowerPoint tutorials
Histology of the Male reproductive tract