Appendix - Anatomy & Physiology

Introduction

Or caecal (cecal) patch

Present in rabbits, the appendix is a primary lymphoid tissue located at the ileocaecal junction and is part of the mucosal-associated lymphoid tissues (MALT) and more specifically the gut-associated lymphoid tissue (GALT).

Development

Lymphatic tissue develops during early life reaching maximum size during early adulthood. Some regression (involution) occurs as the animal ages but is not complete.

Structure

The appendix is a blind ending out pouching of the caeca at the ileocaecal junction in the intestines. The lamina propria of the appendix contains a high number of lymphocytes as well as having a number of lymphatic nodules.

Function

The appendix is a bursa equivalent organ and consequently has functions associated with maturation and differentiation of B lymphocytes.

Originally funded by the RVC Jim Bee Award 2007

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