Heart Failure, Diagnosis
A number of diagnostic procedures need to be taken into account when diagnosing heart failure.
History & Clinical Signs
Coughing, dyspnea, tachypnea, orthopnea, exercise intolerance, syncope, lethargy, peripheral oedma, ascites, mucous membrane colour and weight loss are all clinical signs that may be caused by heart disease, but may also have other causes. There may also be a capillary refill time of less than 3 seconds, which is normal. Over 3 seconds is abnormal. Pale mucous membranes suggest poor peripheral circulation due to vasoconstriction, decreased hemoglobin in the blood (anaemia), or shock. Cyanosis suggests adequate hemoglobin, but inadequate oxygenation. This can be seen with pleural effusion/pulmonary oedema - right to left shunt within the circulation causing deoxygenated blood to mix with oxygenated blood.
Signs of heart failure are directly related to which side is affected. The above signs are characteristic of cardiac problems, but can also be the signs of other diseases involving different body systems therefore a good physical exam including signalment, history, observation, palpation, percussion, and auscultation are necessary to identify true cardiac problems.
Physical Exam
Felines often present acutely with no history of heart disease. They commonly throw blood clots to the aorta which lodge in the bifurcation just before entering the rear limbs. The presence of no palpable femoral pulses and cold limbs along with pulmonary edema and/or pleural effusion is strongly supportive of heart failure.
Observation
Clinical signs as described above.
Palpation
Precordium: (Left side of the chest behind the elbow where heart contractions are easily palpated and auscultated). Heart rate, rhythm, character, apex beat and palpable thrill can all be detected here.
Pulse: (rate, rhythm, character). Dog: Femoral pulse; palpate heart, Horse: External maxillary/ facial artery; transverse facial artery; median artery; digital artery; metatarsal artery, Cattle: external maxillary/ facial artery; middle coccygeal artery; median artery.
Pulse Deficits (seen with arrhythmias)
Jugular pulses and/or jugular venous distension and/or enlarged ventral abdominal veins (indicates high venous pressure).
Abdomen: pitting oedema, ascites, splenomegaly, hepatomegaly and fluid thrill (fluid movement causes a palpable vibration).
Percussion
A method of diagnosis performed by flicking a body part with fingers and the resulting sound helps determine size, position, and density of the underlying structures. The thorax will have a lack of resonance if the lung has solidified and you will be able to detect a fluid line. The abdomen will show a fluid thrill on percussion.
Auscultation
A method of diagnosis performed by listening to sounds inside the body. Auscultation can be performed with or without a stethoscope. Abdominal, cardiac, pulmonary, and thoracic auscultation can all be performed. Cardiac auscultation is used to listen to heart sounds and heart murmurs.
Heart Sounds:
- These differ with different species. In the dog and cat normal heart sounds are S1 (closure of atrioventricular valves; heard best at left heart apex) and S2 (closure of semilunar valves; heard best at left heart base); Lub-Dup sound. Abnormal Heart Sounds: S3 & S4 occur during diastole and should not be audible in dogs and cats. If either one is present, this is called a GALLOP RHYTHM and suggests poor ventricular filling. Du-Lub-Dup sound.
- In the horse normal heart sounds are S1 & S2, S3 & S4; S3 is audible in many horses and marks the end of ventricular filling.
- In the bovid, normal heart sounds are S1 & S2, S4; Healthy farm animals do not have an audible S3 as in the horse.
Heart Murmurs are abnormal heart sounds due to turbulent blood flow. Heart murmurs are characterized based on their timing, location, intensity, radiation, pitch, and shape.
Pulmonary edema will have crackles present in the lungs.
Pleural effusion will have dull lungs songs, more so ventrally.
Electrocardiography (ECG)
This can be used to recognise conduction problems or arrhythmias but is not needed in the diagnosis of heart failure.
Radiology
Will show cardiac enlargement +/- right-sided heart failure signs, which are ascites, hepatomegaly and pleural effusion and left sided heart failure signs which are pulmonary oedema and pulmonary venous distension.
Echocardiography
Can be used to determine the cause of heart failure, such as structural deformities etc. Right parasternal short axis view (mushroom view) can provide quick insight into general volume status as well as ventricle thickness and ratio giving even a novice observer some idea as to cardiac vs non cardiac disease.
Pericardial effusion can also be ruled out
Blood clots can be seen in the left atrium sometimes.
Ultrasound
TFAST and VetBLUE can be used to quickly determine if edema is present in the lungs or effusion is present in the pleural cavity, thus differentiating it from "dry" lung diseases such as asthma. Presence of nodules is indicative of fungal or neoplastic disease. If the lungs are dry, there is no left sided congestive heart failure present by definition.
The vena cava can be evaluated as it crosses the diaphragm. Distension is diagnostic for volume overload or right sided heart failure.
Cardiac Markers
NT-pro BNP levels can be measured in house or sent out to lab to measure heart muscle stretch. This cane be applied as a screening test for at risk breeds or as a diagnostic tool in emergencies or when other tests do not provide a clear answer.
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References
Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) Bovine Medicine (Second edition), Blackwell Publishing
Blood, D.C. and Studdert, V. P. (1999) Saunders Comprehensive Veterinary Dictionary (2nd Edition) Elsevier Science
Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) W.B. Saunders Company
Ettinger, S.J, Feldman, E.C. (2005) Textbook of Veterinary Internal Medicine (6th edition, volume 2) W.B. Saunders Company
Fossum, T. W. et. al. (2007) Small Animal Surgery (Third Edition) Mosby Elsevier
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial
Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier
Radostits, O.M, Arundel, J.H, and Gay, C.C. (2000) Veterinary Medicine: a textbook of the diseases of cattle, sheep, pigs, goats and horses Elsevier Health Sciences
Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) Equine Internal Medicine (Third Edition), Saunders
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