Equine Rhinopneumonitis

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  • Causative agent: equine herpesvirus type 1 and type 4
  • Primary viral lesions in nasal mucosa and lungs
  • Mild, transient bronchointerstitial pneumonia
  • Latent infection acting as a reservoir
  • Sites of latency: bronchial lymph nodes and trigeminal ganglia
  • Replicates in upper respiratory tract epithelium
  • Disseminated to lower respiratory tract
  • Transported to other organs in T-lymphocytes - viraemia up to 3 weeks
  • Vasculitis, abortion
  • May be accompanied by secondary bacterial infection