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* The CTl killing mechanism is initiated by direct CTL-target cell contact.   
 
* The CTl killing mechanism is initiated by direct CTL-target cell contact.   
* The cells involved bind by antigen/MHC class I-TcR interaction.
+
* The cells involved bind by antigen/[[Adaptive Immune System - WikiBlood#Structure and Function of MHC Class I|MHC]]
 +
class I-TcR interaction.
 
** This results in the CTL's intracellular granules becoming localised to the area of contact.  
 
** This results in the CTL's intracellular granules becoming localised to the area of contact.  
 
*** These granules contain most of the molecules responsible for cytotoxicity.  
 
*** These granules contain most of the molecules responsible for cytotoxicity.  
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*** Proteolytic enzymes.
 
*** Proteolytic enzymes.
 
*** Target cell nucleases.
 
*** Target cell nucleases.
*** Cause programmed cell death.  
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*** Cause programmed cell death.
    
==T-Cell Activation==
 
==T-Cell Activation==
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