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The crest neuroectoderm is the region at the junction of epidermis and neural plate. When the neural tube closes, the epidermis is brought into contact with the crest neuroectoderm. This contact causes cells of the crest neuroectoderm to undergo an epithelial to mesenchymal transition. Cells that undergo this transition break away from the neuroectoderm and are called '''neural crest cells'''. The peripheral nervous system (PNS) develops from the neural crest. The undifferentiated neural crest cells migrate away from the neural tube along "pathways". These pathways are governed by repulsive cues from ther cells, as well as proliferation and survival signals, they differentiate once they reach their destination. Other non - neural tissues also develop from the neural crest. The type of tissue that neural crest forms is dependant on the origination of the cell along the anterior - posterior axis:

The crest neuroectoderm is the region at the junction of epidermis and neural plate. When the neural tube closes, the epidermis is brought into contact with the crest neuroectoderm. This contact causes cells of the crest neuroectoderm to undergo an epithelial to mesenchymal transition. Cells that undergo this transition break away from the neuroectoderm and are called '''neural crest cells'''. The peripheral nervous system (PNS) develops from the neural crest. The undifferentiated neural crest cells migrate away from the neural tube along "pathways". These pathways are governed by repulsive cues from ther cells, as well as proliferation and survival signals, they differentiate once they reach their destination. Other non - neural tissues also develop from the neural crest. The type of tissue that neural crest forms is dependant on the origination of the cell along the anterior - posterior axis:

'''Anterior Neural Crest''' forms; sensory neurones and [[PNS Structure - Anatomy & Physiology#Schwann Cells|schwann cells]]; [[Bones and Cartilage - Anatomy & Physiology|bones]] of the head; dermis of the face; and [[Bones and Cartilage - Anatomy & Physiology|cartilage]].

'''Anterior Neural Crest''' forms; sensory neurones and [[PNS Structure - Anatomy & Physiology#Schwann Cells|schwann cells]]; [[Bones - Anatomy & Physiology|bones]] of the head; dermis of the face; and [[Cartilage - Anatomy & Physiology|cartilage]].

'''Trunk Neural Crest''' forms; sensory neurones of the somatic and autonomic nervous systems (ANS); sympathetic motor neurones of the ANS and melanocytes.

'''Trunk Neural Crest''' forms; sensory neurones of the somatic and autonomic nervous systems (ANS); sympathetic motor neurones of the ANS and melanocytes.