Difference between revisions of "Joint Response to Injury"
Jump to navigation
Jump to search
m (Text replace - "[[Disorders of Cell Growth - Pathology" to "[[Cell Growth Disorders") |
|||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
| + | {{review}} | ||
| + | |||
| + | {{toplink | ||
| + | |backcolour =CDE472 | ||
| + | |linkpage =Musculoskeletal System - Pathology | ||
| + | |linktext =Musculoskeletal System | ||
| + | |maplink = Musculoskeletal System (Content Map) - Pathology | ||
| + | |pagetype =Pathology | ||
| + | |sublink1=Joints - Pathology | ||
| + | |subtext1=JOINTS | ||
| + | }} | ||
| + | <br> | ||
===Causes of injury === | ===Causes of injury === | ||
| Line 20: | Line 32: | ||
*Synovial membranes respond by: | *Synovial membranes respond by: | ||
**Villous hypertrophy | **Villous hypertrophy | ||
| − | ***+/- synovitis | + | ***+/- [[Joints Inflammatory - Pathology|synovitis]] |
**Hyperplasia | **Hyperplasia | ||
| − | |||
| − | |||
| − | |||
Revision as of 12:49, 15 February 2011
 |
This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
|
Causes of injury
- Trauma
- Instability
- Lubrication failure
- Infectious organisms
- Immune-mediated disease
Reaction to injury
- Articular cartilage has limited ability to regenerate
- Superficial defects are long standing
- Chondrocyte hyperplasia is ineffective at filling the defect
- Non-painful
- Defects reaching subchondral bone
- Filled with vascular fibroous tissue undergoing metaplasia into cartilage
- Painful
- Fibrillation - loss of proteoglycans -> condensation of collagen fibres -> fraying of surface
- Eburnation - loss of articular cartilage -> exposure of subchondral bone -> becomes dense and polished
- Superficial defects are long standing
- Synovial membranes respond by:
- Villous hypertrophy
- +/- synovitis
- Hyperplasia
- Villous hypertrophy