Changes

As disease progresses, multisystemic signs develop:  

As disease progresses, multisystemic signs develop:  

'''Cardiovascular'''– Tachycardia, Petechiae and Ecchymoses, [[Anaemia]]

'''Cardiovascular''' – Tachycardia, Petechiae and Ecchymoses, [[Anaemia]]

'''Respiratory'''- Nasal discharge, Dyspnoea, Cough

'''Respiratory''' - Nasal discharge, Dyspnoea, Cough

'''Gastrointestinal'''– [[Diarrhoea]] with mucus and/or blood, Inappetance, Hypomotility, Constipation

'''Gastrointestinal''' – [[Diarrhoea]] with mucus and/or blood, Inappetance, Hypomotility, Constipation

'''Opthalmological'''– Blindness, Nystagmus, Corneal oedema, Discharge, Photophobia, Increased lacrimation

'''Opthalmological''' – Blindness, Nystagmus, Corneal oedema, Discharge, Photophobia, Increased lacrimation

'''Reproductive'''– Abortion, Stillbirths, Agalactia

'''Reproductive''' – Abortion, Stillbirths, Agalactia

'''Urinary'''– Red, brown or pink urine, Haemoglobinuria, Myoglobinuria

'''Urinary''' – Red, brown or pink urine, Haemoglobinuria, Myoglobinuria

'''Dermatological'''– Pruritus, Plaques, Wheals, Papules, Oedema, Subcutaneous masses

'''Dermatological''' – Pruritus, Plaques, Wheals, Papules, Oedema, Subcutaneous masses

'''Other'''– Sudden death, [[Icterus]],  Marked Pyrexia, Neurological signs, Emaciation

'''Other''' – Sudden death, [[Icterus]],  Marked Pyrexia, Neurological signs, Emaciation

The clinical phase usually lasts '''2-3 weeks''', but death occasionally occurs within a week.

The clinical phase usually lasts '''2-3 weeks''', but death occasionally occurs within a week.