Difference between revisions of "Angiotensin Converting Enzyme"

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==Overview==
  
ACE
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Angiotensin converting enzyme is known as '''ACE'''. It is a membrane bound '''metalloproteinase''' and converts Angiotensin 1 to Angiotensin 2.
* Membrane bound metalloproteinase
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[[Image:angiotensin.png|right|thumb|250px|Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).]]
* Converts Angiotensin 1 to Angiotensin 2
 
* Very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]
 
* Predominantly expressed on epithelial cell membranes in the pulmonary ciculation
 
* The site of action of the group of drugs - ACE inhibitors
 
  
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It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary circulation and this is therefore, the site of action of the ACE inhibitor drugs.
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[[Category:Kidney Hormonal Regulators]]
 
[[Category:Kidney Hormonal Regulators]]
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[[Category:To Do - AimeeHicks]]

Latest revision as of 08:15, 20 October 2016


Overview

Angiotensin converting enzyme is known as ACE. It is a membrane bound metalloproteinase and converts Angiotensin 1 to Angiotensin 2.

Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).


It is very important in the Renin Angiotensin Aldosterone System (RAAS). ACE is predominantly expressed on epithelial cell membranes in the pulmonary circulation and this is therefore, the site of action of the ACE inhibitor drugs.



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