694
edits
Changes
no edit summary
The total body content of sodium is regulated rather than the actual plasma concentration. It would be impossible to regulate actual plasma concentration for 3 reasons:
The total body content of sodium is regulated rather than the actual plasma concentration. It would be impossible to regulate actual plasma concentration for 3 reasons:
* When sodium is reabsorbed water follows it so the volume of the plasma is altered rather than the concentration of sodium changing
* When sodium is reabsorbed water follows it so the volume of the plasma is altered rather than the concentration of sodium changing
* [[Renin Angiotensin Aldosterone System#Effects of Angiotensin 2 On Sodium|Angiotensin 2]] and [[Aldosterone|Aldosterone]] affect sodium but they also affect ECF volume so only quantity affected not concentration
* [[Renin Angiotensin Aldosterone System#Effects of Angiotensin 2 On Sodium|Angiotensin 2]] and [[Aldosterone|aldosterone]] affect sodium but they also affect ECF volume so only quantity affected not concentration
* [[Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland | ADH]] and thirst response also work together to dilute the ECF if concentrations of sodium are high so although there is more NaCl the actual concentration is not really changed.
* [[Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland | ADH]] and thirst response also work together to dilute the ECF if concentrations of sodium are high so although there is more NaCl the actual concentration is not really changed.
The kidneys are the most important regulatory organs of sodium in the body. They adjust their excretion to match the amount taken in through the digestive tract taking into account the amount lost through sweat. The handling of sodium by the kidneys is also essential to allow the reabsorption of many other important nutrients which would otherwise be lost in the urine. These nutrients include glucose, amino acids, chloride, bicarbonate and phosphate. It is also exchanged for the likes of potassium and hydrogen ions to aid in their secretion. As a result sodium transport accounts for over 80% of the energy metabolism in the kidneys
The kidneys are the most important regulatory organs of sodium in the body. They adjust their excretion to match the amount taken in through the digestive tract taking into account the amount lost through sweat. The handling of sodium by the kidneys is also essential to allow the reabsorption of many other important nutrients which would otherwise be lost in the urine. These nutrients include glucose, amino acids, chloride, bicarbonate and phosphate. It is also exchanged for the likes of potassium and hydrogen ions to aid in their secretion. As a result sodium transport accounts for over 80% of the energy metabolism in the kidneys
[[Category:Electrolytes]]
[[Category:Electrolytes]]