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[[Image:Heterophil.jpg|150px|thumb|right|'''Heterophil''' (Copyright © RVC. All rights reserved)]]
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==Introduction==
 
==Introduction==
Heterophils are the most abundant '''granulocyte''' in most '''avian species''' and occur alongside lymphocytes, monocytes, eosinophils and basophils in avian blood. These cells are also found in some '''reptile and mammalian species'''.
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[[Image:Heterophil.jpg|150px|thumb|right|'''Heterophil''' (Copyright © RVC)]]
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Heterophils are the most abundant '''granulocyte''' in most '''avian species''' and occur alongside [[lymphocytes]], [[monocytes]], [[eosinophils]] and [[basophils]] in avian blood. These cells are also found in some '''reptile and mammalian species'''.
    
==Development==
 
==Development==
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==Changes==
 
==Changes==
===Immature heterophils===
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===Immature Heterophils===
 
These have '''increased cytoplasmic basophilia''', '''non-segmented nuclei''' and '''immature granules''' compared with normal, mature heterophils.
 
These have '''increased cytoplasmic basophilia''', '''non-segmented nuclei''' and '''immature granules''' compared with normal, mature heterophils.
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'''Band heterophils''' resemble mature heterophils, except that the nucleus is not lobed. The nucleus is often hidden behind the cytoplasmic granules, and it can be difficult to identify a band heterophil. Special stains can help with this.
 
'''Band heterophils''' resemble mature heterophils, except that the nucleus is not lobed. The nucleus is often hidden behind the cytoplasmic granules, and it can be difficult to identify a band heterophil. Special stains can help with this.
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===Toxic heterophils===
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===Toxic Heterophils===
 
Heterophils exhibit '''toxic changes in response to severe systemic illness'''.
 
Heterophils exhibit '''toxic changes in response to severe systemic illness'''.
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{{Learning
 
{{Learning
|flashcards = [[Avian Medicine Q&A 21]]
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|flashcards = [[Avian Medicine Q&A 21]]<br>[[Reptiles and Amphibians Q&A 11]]
 
}}
 
}}
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Feldman, B. (2000) '''Schalm's Veterinary haematology''' ''Wiley-Blackwell''
 
Feldman, B. (2000) '''Schalm's Veterinary haematology''' ''Wiley-Blackwell''
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Frye, FL & Williams, DL (1995) '''Self-Assessment Colour Review - Reptiles & Amphibians''' ''Manson''
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{{review}}
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==Webinars==
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<rss max="10" highlight="none">https://www.thewebinarvet.com/clinical-pathology/webinars/feed</rss>
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[[Category:To Do - Helen]]
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[[Category:To Do - Review]]
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[[Category:Expert Review - Bird]]
 
[[Category:Blood Cells]]
 
[[Category:Blood Cells]]
 
[[Category:Lizard_and_Snake_Glossary]]
 
[[Category:Lizard_and_Snake_Glossary]]
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[[Category:Expert Review - Exotics]]