Difference between revisions of "Pancreas - Anatomy & Physiology - Flashcards"
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|subtext2=PANCREAS | |subtext2=PANCREAS | ||
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− | + | <FlashCard questions="37"> | |
− | + | |q1=What type of gland is the pancreas? | |
− | + | |a1=Tubuloalveolar | |
− | + | |l1=Pancreas - Anatomy & Physiology#Introduction | |
− | + | |q2=From which embryological germ layer does the pancreas develop from? | |
− | |- | + | |a2=Endoderm, except the connective tissue which develops from splanchnic mesoderm |
− | | | + | |l2=Pancreas - Anatomy & Physiology#Development |
− | || | + | |q3=Does the pancreatic duct develop from the dorsal or ventral bud? |
− | + | |a3=Ventral | |
− | + | |l3=Pancreas - Anatomy & Physiology#Development | |
− | + | |q4=Where do the ducts of the pancreas open into? | |
− | + | |a4=Duodenum; the pancreatic duct opens at the major duodenal papilla with the bile duct; the accessory duct opens at the minor duodenal papilla | |
− | | | + | |l4=Pancreas - Anatomy & Physiology#Structure |
− | + | |q5=What are the functions of the exocrine part of the pancreas? | |
− | | | + | |a5=Produces a secretion that is alkaline to neutralise stomach acid and contains enzymes for digestion |
− | | | + | |l5=Pancreas - Anatomy & Physiology#Exocrine Function |
− | + | |q6=Which ions are present within the secretion of the pancreas? | |
− | | | + | |a6=Bicarbonate and chloride |
− | + | |l6=Pancreas - Anatomy & Physiology#Exocrine Function | |
− | + | |q7=Why does stomach acid need to be neutralised? | |
− | + | |a7=To provide the optimum pH for pancreatic enzymes, to prevent damage to the thin, absorptive mucosa of the duodenum and to buffer the large intestine | |
− | + | |l7=Pancreas - Anatomy & Physiology#Exocrine Function | |
− | | | + | |q8=Name the cell types present in the islets of Langerhans |
− | + | |a8=Alpha, beta, delta and F cells | |
− | | | + | |l8=Pancreas - Anatomy & Physiology#Histology |
− | | | + | |q9=What is the antagonist hormone to insulin and what does it do? |
− | | | + | |a9=Glucagon, it raises blood glucose level |
− | | | + | |l9=Pancreas - Anatomy & Physiology#Endocrine Function |
− | + | |q10=What is the function of somatostatin? | |
− | || | + | |a10=It inhibits glucagon and insulin secretion |
− | |- | + | |l10=Pancreas - Anatomy & Physiology#Endocrine Function |
− | | | + | |q11=What effect does parasympathetic innervation have on glucagon secretion? |
− | || | + | |a11=Increases it |
− | + | |l11=Pancreas - Anatomy & Physiology#Glucagon | |
− | + | |q12=What effect does glucagon have on body reserves? | |
− | |- | + | |a12=Catabolic |
− | | | + | |l12=Pancreas - Anatomy & Physiology#Glucagon |
− | || | + | |q13=Which shape is the horse's pancreas? |
− | + | |a13=Triangular | |
− | | | + | |l13=Pancreas - Anatomy & Physiology#Equine |
− | | | + | |q14=What is the main target tissue of glucagon? |
− | | | + | |a14=Liver |
− | | | + | |l14=Pancreas - Anatomy & Physiology#Glucagon |
− | + | |q15=What other tissues does glucagon have an effect on? | |
− | | | + | |a15=Skeletal muscle and adipose tissue |
− | | | + | |l15=Pancreas - Anatomy & Physiology#Glucagon |
− | | | + | |q16=Which enzyme does glucagon inactivate in glycolysis? |
− | | | + | |a16=Pyruvate kinase |
− | + | |l16=Pancreas - Anatomy & Physiology#Glucagon | |
− | || | + | |q17=How does glucagon inactivate this enyme? |
− | | | + | |a17=Phosphorylation via PKA |
− | + | |l17=Pancreas - Anatomy & Physiology#Glucagon | |
− | | | + | |q18=What effect does glucagon have on adipose tissue? |
− | + | |a18=Increases β oxidation of fatty acids | |
− | + | |l18=Pancreas - Anatomy & Physiology#Glucagon | |
− | | | + | |q19=What effect does glucagon have on skeletal muscle? |
− | | | + | |a19=Increases the rate of protein catabolism |
− | | | + | |l19=Pancreas - Anatomy & Physiology#Glucagon |
− | + | |q20=How may ketosis occur during fasting? | |
− | | | + | |a20=The citric acid cycle turns slowly as oxaloacetate is removed to make glucose. Acetyl CoA builds up and is converted to ketone bodies |
− | |- | + | |l20=Pancreas - Anatomy & Physiology#Glucagon |
− | | | + | |q21=Describe the structure of insulin. |
− | || | + | |a21=A & B chains linked by disulphide bridges |
− | + | |l21=Pancreas - Anatomy & Physiology#Insulin | |
− | | | + | |q22=Describe the mechanism that causes insulin to be released. |
− | |- | + | |a22=Glucose enters the β cell through GLUT 2 and is metabolised. ATP depolarises the plasma membrane which leads to calcium signalling causing release of insulin |
− | | | + | |l22=Pancreas - Anatomy & Physiology#Insulin |
− | | | + | |q23=How does insulin enable glucose to be taken up by heptaocytes, adipocytes and skeletal muscle? |
− | + | |a23=It causes expression of GLUT 4 | |
− | | | + | |l23=Pancreas - Anatomy & Physiology#Insulin |
− | | | + | |q24=What effect does insulin have on basal metabolic rate? |
− | | | + | |a24=Increases it in all cells |
− | | | + | |l24=Pancreas - Anatomy & Physiology#Insulin |
− | + | |q25=What are the clinical signs of diabetes mellitus? | |
− | | | + | |a25=Glucosuria, polyuria, polydipsia, polyphagia, weight loss, ketosis and ketonuria |
− | | | + | |l25=Pancreas - Anatomy & Physiology#Diabetes Mellitus |
− | | | + | |q26=What are the two causes of diabetes mellitus in dogs? |
− | | | + | |a26=β cell deficiency (mainly) and insulin antagonism |
− | + | |l26=Pancreas - Anatomy & Physiology#Diabetes Mellitus | |
− | | | + | |q27=How many ducts of the pancreas does the cat have? |
− | | | + | |a27=One, the pancreatic duct |
− | + | |l27=Pancreas - Anatomy & Physiology#Carnivore | |
− | | | + | |q28=In which animal group in particular is there a constant secretion of pancreatic juice? |
− | + | |a28=Ruminants | |
− | + | |l28=Pancreas - Anatomy & Physiology#Ruminants | |
− | |- | + | |q29=What are the two types of diabetes in cats? |
− | | | + | |a29=IDDM and NIDDM |
− | || | + | |l29=Pancreas - Anatomy & Physiology#Diabetes Mellitus |
− | + | |q30=What are the two arteries that supply blood to the pancreas? | |
− | + | |a30=Coeliac (left lobe) and cranial mesenteric (right lobe) | |
− | |- | + | |l30=Pancreas - Anatomy & Physiology#Insulin |
− | | | + | |q31=Which hormones increase pancreatic secretion? |
− | | | + | |a31=CCK, secretin and gastrin |
− | + | |l31=Pancreas - Anatomy & Physiology#Innervation | |
− | | | + | |q32=Which lymph nodes does lymph from the pancreas drain into? |
− | + | |a32=Pancreatoduodenal | |
− | + | |l32=Pancreas - Anatomy & Physiology#Lymphatics | |
− | || | + | |q33=Describe the components of the exocrine pancreas. |
− | + | |a33=Acini, which consist of 40-50 pyramidal epithelial cells which drain into a lumen | |
− | || | + | |l33=Pancreas - Anatomy & Physiology#Histology |
− | | | + | |q34=What is present in the apex of the epithelial cells? |
− | | | + | |a34=Secretory granules containing the zymogen precursors of the pancreatic enzymes |
− | + | |l34=Pancreas - Anatomy & Physiology#Histology | |
− | + | |q35=Which cell type in the islet of Langerhan's produce somatostatin? | |
− | + | |a35=δ cells | |
− | + | |l35=Pancreas - Anatomy & Physiology#Histology | |
− | + | |q36=Where does the right lobe of the pancreas exits? | |
− | + | |a36=Mesoduodenum | |
− | + | |l36=Pancreas - Anatomy & Physiology#Carnivore | |
− | + | |q37=In the dog, which of the two ducts of the pancreas is bigger? | |
− | + | |a37=Accessory | |
− | + | |l37=Pancreas - Anatomy & Physiology#Carnivore | |
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Revision as of 00:27, 18 February 2010
|
Question | Answer | Article | |
What type of gland is the pancreas? | Tubuloalveolar
|
Link to Article | |
From which embryological germ layer does the pancreas develop from? | Endoderm, except the connective tissue which develops from splanchnic mesoderm
|
Link to Article | |
Does the pancreatic duct develop from the dorsal or ventral bud? | Ventral
|
Link to Article | |
Where do the ducts of the pancreas open into? | Duodenum; the pancreatic duct opens at the major duodenal papilla with the bile duct; the accessory duct opens at the minor duodenal papilla
|
Link to Article | |
What are the functions of the exocrine part of the pancreas? | Produces a secretion that is alkaline to neutralise stomach acid and contains enzymes for digestion
|
Link to Article | |
Which ions are present within the secretion of the pancreas? | Bicarbonate and chloride
|
Link to Article | |
Why does stomach acid need to be neutralised? | To provide the optimum pH for pancreatic enzymes, to prevent damage to the thin, absorptive mucosa of the duodenum and to buffer the large intestine
|
Link to Article | |
Name the cell types present in the islets of Langerhans | Alpha, beta, delta and F cells
|
Link to Article | |
What is the antagonist hormone to insulin and what does it do? | Glucagon, it raises blood glucose level
|
Link to Article | |
What is the function of somatostatin? | It inhibits glucagon and insulin secretion
|
Link to Article | |
What effect does parasympathetic innervation have on glucagon secretion? | Increases it
|
Link to Article | |
What effect does glucagon have on body reserves? | Catabolic
|
Link to Article | |
Which shape is the horse's pancreas? | Triangular
|
Link to Article | |
What is the main target tissue of glucagon? | Liver
|
Link to Article | |
What other tissues does glucagon have an effect on? | Skeletal muscle and adipose tissue
|
Link to Article | |
Which enzyme does glucagon inactivate in glycolysis? | Pyruvate kinase
|
Link to Article | |
How does glucagon inactivate this enyme? | Phosphorylation via PKA
|
Link to Article | |
What effect does glucagon have on adipose tissue? | Increases β oxidation of fatty acids
|
Link to Article | |
What effect does glucagon have on skeletal muscle? | Increases the rate of protein catabolism
|
Link to Article | |
How may ketosis occur during fasting? | The citric acid cycle turns slowly as oxaloacetate is removed to make glucose. Acetyl CoA builds up and is converted to ketone bodies
|
Link to Article | |
Describe the structure of insulin. | A & B chains linked by disulphide bridges
|
Link to Article | |
Describe the mechanism that causes insulin to be released. | Glucose enters the β cell through GLUT 2 and is metabolised. ATP depolarises the plasma membrane which leads to calcium signalling causing release of insulin
|
Link to Article | |
How does insulin enable glucose to be taken up by heptaocytes, adipocytes and skeletal muscle? | It causes expression of GLUT 4
|
Link to Article | |
What effect does insulin have on basal metabolic rate? | Increases it in all cells
|
Link to Article | |
What are the clinical signs of diabetes mellitus? | Glucosuria, polyuria, polydipsia, polyphagia, weight loss, ketosis and ketonuria
|
Link to Article | |
What are the two causes of diabetes mellitus in dogs? | β cell deficiency (mainly) and insulin antagonism
|
Link to Article | |
How many ducts of the pancreas does the cat have? | One, the pancreatic duct
|
Link to Article | |
In which animal group in particular is there a constant secretion of pancreatic juice? | Ruminants
|
Link to Article | |
What are the two types of diabetes in cats? | IDDM and NIDDM
|
Link to Article | |
What are the two arteries that supply blood to the pancreas? | Coeliac (left lobe) and cranial mesenteric (right lobe)
|
Link to Article | |
Which hormones increase pancreatic secretion? | CCK, secretin and gastrin
|
Link to Article | |
Which lymph nodes does lymph from the pancreas drain into? | Pancreatoduodenal
|
Link to Article | |
Describe the components of the exocrine pancreas. | Acini, which consist of 40-50 pyramidal epithelial cells which drain into a lumen
|
Link to Article | |
What is present in the apex of the epithelial cells? | Secretory granules containing the zymogen precursors of the pancreatic enzymes
|
Link to Article | |
Which cell type in the islet of Langerhan's produce somatostatin? | δ cells
|
Link to Article | |
Where does the right lobe of the pancreas exits? | Mesoduodenum
|
Link to Article | |
In the dog, which of the two ducts of the pancreas is bigger? | Accessory
|
Link to Article |