Difference between revisions of "Category:Haemophilus species"

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Overview

• Inhabit mucosal epithelium of upper respiratory and lower genital tract
• Suppurative infections due to release of pro-inflammatory cytokines released from macrophages
• Serofibrinous to fibrinopurative infections of lungs, body cavities and joints
• Colonisation of meningeal vessels causes a thrombotic vasculitis leading to encephalitis and meningitis

Haemophilus characteristics

• Morphologically variable Gram-negative bacilli, ranging from short rods to long filaments
• Facultative anaerobes
• Typically oxidase positive
• Depend on beta-nicotinamide adenine dinucleotide (NAD) (V factor) and/or Haemin (X fector) for growth
• Heated blood agar (Chocolate Agar) required for growth of NAD-dependent strains
• Haemin-dependent strains grow on Blood Agar
• Do not grow on MacConkey agar

Haemophilus parasuis

Haemophilus somnus

• Cattle
  • Haemophilus sommus in Enzootic pneumonia of calves
  • Septicaemia
  • Causes infectious thromboencephalitis, bronchopneumonia and sporadic reproductive tract infections in cattle 1-3 years old
  • Found in the USA and Europe, including UK
  • Causes a meningoencephalitis with fibrinous arterial thrombosis and necrosis
  • Causes fever, staggering and dyspnoea, progressing to somnolence, paralysis and death
  • Mortality can be high
• Sheep
  • Epididymitis in young rams
  • Vulvitis, mastitis and reduced reproductive performance in ewes
  • Septicaemia, arthritis, meningitis and pneumonia in lambs

Haemophilus pleuropneumonia

• H. pleuropneumonia in Contagious porcine pleuropneumonia

Haemophilus paragalinarum

• Infectious coryza of poultry - accute upper-respiratory tract infection
• Nasal discharge, swollen sinuses, facial oedema and conjunctivitis
• Resistant to complement-mediated lysis and phagocytosis

Haemophilus haemoglobinophilus

• Commensal of canine lower genital tract
• Causes cystitis and neonatal infections

Haemophilus felis

• Associated with feline conjunctivitis

Haemophilus influenzae

• Human meningitis, septicaemia, bronchopneumonia, conjunctivitis, epiglottitis, and otitis