Difference between revisions of "Zygomycosis"
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*Infection is by inhalation and ingestion | *Infection is by inhalation and ingestion | ||
− | *Infects [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] of the [[Cardiorespiratory System | + | *Infects [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] of the [[Cardiorespiratory System - Anatomy & Physiology|respiratory]] and [[Alimentary - Anatomy & Physiology|alimentary tract]] |
**[[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] enlarge and become caseous | **[[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] enlarge and become caseous | ||
− | **Can cause [[Alimentary | + | **Can cause [[Alimentary - Anatomy & Physiology#Stomach|stomach]] and [[Small Intestine - Anatomy & Physiology|intestinal]] ulcers |
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*Cattle | *Cattle | ||
**Bronchial, mesenteric and mediastinal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] lesions | **Bronchial, mesenteric and mediastinal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] lesions | ||
− | **Ulcers of the [[Nasal | + | **Ulcers of the [[Nasal cavity - Anatomy & Physiology|nasal cavity]] and [[The Abomasum - Anatomy & Physiology|abomasum]] also occur |
− | **Often contaminate the [[Placenta - Anatomy & Physiology|placenta]] | + | **Often contaminate the [[Gestation -Placenta - Anatomy & Physiology|placenta]] |
*Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected | *Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected | ||
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Image:Sporangiospores.jpg|<center><p>'''Sporangiospores'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery> | Image:Sporangiospores.jpg|<center><p>'''Sporangiospores'''</p><sup>Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath</sup></center></gallery> | ||
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[[Category:Systemic_Mycoses]] | [[Category:Systemic_Mycoses]] | ||
[[Category:To_Do_-_Fungi]] | [[Category:To_Do_-_Fungi]] | ||
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Revision as of 11:29, 25 June 2010
- Also known as mucormycosis, hyphomycosis and phycomycosis
- Caused by strains of Mucor, Absidia, Rhizopus and Mortierella
- Mucor circinelloides(rare), Rhizomucor pusillus and R. meihi
- Absidia corymbifera often causes zygomycosis in cattle and pigs
- Rhizopus arrhizus, R. microsporus and R. rhizopodormis
- Mortierella wolfi implicated in bovine abortion (mycotic placentitis), M. hygrophila in fowl and M.polycephala in cattle
- Occurs widely in nature
- Infection is by inhalation and ingestion
- Infects lymph nodes of the respiratory and alimentary tract
- Lymph nodes enlarge and become caseous
- Can cause stomach and intestinal ulcers
- Granulomatous lesions which can ulcerate
- Mostly localised lesions but can be generalised
- Pigs
- Mediastinal and submandibular lymph nodes lesions
- Embolic tumours in the liver and lungs
- Can also be present in gastric ulcers
- Cattle
- Bronchial, mesenteric and mediastinal lymph nodes lesions
- Ulcers of the nasal cavity and abomasum also occur
- Often contaminate the placenta
- Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected
- Microscopically:
- Fragments of non-septate hyphae which are branched and coarse
- Rhizomucor produce a thick, grey mycelium and have short, black, spherical sporangia
- Mucor produce thick, colourless mycelium with no rhizoids. Globose spoangia with small spores are present and sporagiospores are simple or branched.
- Absidia resemble Rhizopus grossly
- Mortierella produce white, velvet colonies on Sabouraud's Dextrose and Blood agar
- Grows on Sabauraud's Dextrose agar
- Common contaminants
- Treatment is with Amphotericin B
- Surgery is also an option in treatment