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* [[Lymphocytes - WikiBlood#T cells|T cells]] function only after recent activation by antigen.
 
* [[Lymphocytes - WikiBlood#T cells|T cells]] function only after recent activation by antigen.
* CD4 binds [[MHC - WikiBlood#MHC II|MHC class I]].
+
* CD4 binds [[MHC - WikiBlood#MHC II|MHC class II]].
** [[Lymphocytes - WikiBlood#Helper CD4+|CD4+ T-cells]] therefore recognise antigen only in association with [[MHC - WikiBlood#MHC II|MHC class I]]  
+
** [[Lymphocytes - WikiBlood#Helper CD4+|CD4+ T-cells]] therefore recognise antigen only in association with [[MHC - WikiBlood#MHC II|MHC class II]]  
 
* CD8 binds [[MHC - WikiBlood#MHC I|MHC class I]].
 
* CD8 binds [[MHC - WikiBlood#MHC I|MHC class I]].
 
** [[Lymphocytes - WikiBlood#Cytotoxic CD8+|CD8+ T-cells]] recognise antigen only in association with [[MHC - WikiBlood#MHC I|MHC class I]].  
 
** [[Lymphocytes - WikiBlood#Cytotoxic CD8+|CD8+ T-cells]] recognise antigen only in association with [[MHC - WikiBlood#MHC I|MHC class I]].  
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