Difference between revisions of "Eosinopenia"

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*'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.
 
*'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.
  
Corticosteroids are thought to exert a depressive effect on lymphocytes that usually stimulate eosinophil production.
 
  
[[Category:Haematology Changes]][[Category:To Do - James]]
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Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production.
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[[Category:Haematology Changes]][[Category:To Do - James]][[Category:To Do - Review]]

Revision as of 22:36, 31 August 2010



Description

Eosinopaenia refers to a reduction in the normal number of circulating blood eosinophils. It ocurs most commonly as part of a stress leucocgram and in other situations that result in an increase in the circulating concentration of glucocorticoids:

  • Stress leucogram, with which neutrophilia, monocytosis and lymphopaenia would also be expected.
  • Hyperadrenocorticism (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids.
  • Iatrogenic hyperadrenocorticism caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.


Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production.