Lymphoreticular System - Anatomy & Physiology

()Map\Tab LYMPHATIC SYSTEM (Map/Tab) IMMUNOLOGY

Introduction

Also referred to as the reticuloendothelial system or mononuclear phagocytic system. It is compromised of primary lymphoid organs which are responsible fot the production of lymphocytes and the secondary lymphoid organs which function to provide and environment where Lymphocytes can react to antigen from the tissue fluid, blood and mucosal surfaces.

Primary lymphoid tissues

• Bone marrow
• Thymus
• Bursa of Fabricius
• Foetal Liver

Secondary lymphoid tissues

• Lymph nodes
• Spleen
• Mucosal Associated Lymphoid Tissue (MALT)
  • Appendix/caecal pouch
  • Ileal Peyer's Patch
  • Tonsils

Function

• Removal of senescent cells

• Production of immune cells

Lymphocytes

• High Endothelial Venules (HEV)

B Cells

• B Cell Differentiation and Function

• T Cell Independent and T Cell Dependent Responses

• Immunoglobulin Class Switching

T Cells

• T Cell Differentiation and Function

• Major Histocompatability Complex (MHC) molecule

Lymphatic Circulation

• Lymphatic Vessels

Creators

Asher Allison

Natalie Brown