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Lymphoma (view source)

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[[File:Lymphoma in golden.JPG|right|thumb|200px| Lymphoma in a Golden Retriever (Wikimedia Commons)]]

Lymphoma is caused by malignant clonal expansion of lymphoid cells and most commonly arises from lymphoid tissues including the [[Bone Marrow|bone marrow]], [[Thymus - Anatomy & Physiology|thymus]], [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Spleen - Anatomy & Physiology|spleen]]. Lymphoma is documented to be the most common haematopoietic [[Neoplasia - Pathology|neoplasm]] in dogs.

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'''Classification'''

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:'''Cytological classification'''

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::Well differentiaed (lymphocytic) - The malignant cells represent normal lymphocytes, although in excessive numbers.

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::Poorly differentiated (lymphoblastic) - The malignant cells represent atypical lymphocytic cells with lymphoblastic characteristics.

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:'''Tumour distribution'''

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::Nodular/ follicular - A well organised pattern of slow growth, no metastasis, they are of the B-lymphocyte type

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::Diffuse - Result in effacement of normal lymphoid architecture by a very homogeneous population of lymphoid cells.

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:'''Anatomical classification'''

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::Thymic - Only the [[Thymus - Anatomy & Physiology|thymus]] is affected.

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::Alimentary - Gut and associated lymphoid tissue affected.

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::Multicentric - Widespread involvement of lymph nodes.

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::Cutaneous lymphoma - Usually presents as generalised skin disease, but is a malignant transformation of T cells with a propensity for pithelial sites.

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:'''Type of lymphocyte''' - [[T-cell]], [[B-cel]] or [[NK-cell]]

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:'''Time scale''' - Acute or Chronic

===Dog===

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~~===== Classification=====~~

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* '''Cytological classification'''.

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** Well differentiaed (lymphocytic)

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*** The malignant cells represent normal lymphocytes, although in excessive numbers.

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** Poorly differentiated (lymphoblastic).

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*** The malignant cells represent atypical lymphocytic cells with lymphoblastic characteristics.

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* '''Tumour distribution'''

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** Nodular/ follicular.

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*** A well organised pattern of slow growth.

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*** No metastasis.

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*** Are of the B-lymphocyte type.

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** Diffuse.

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*** Result in effacement of normal lymphoid architecture by a very homogeneous population of lymphoid cells.

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* '''Anatomical classification'''

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** Thymic.

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** Only the [[Thymus - Anatomy & Physiology|thymus]].

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** Alimentary.

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*** Gut and associated lymphoid tissue.

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** Multicentric.

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*** Widespread involvement of lymph nodes.

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** Cutaneous lymphoma.

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*** Usually presents as generalised skin disease, but is a malignant transformation of T cells with a propensity for pithelial sites

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* '''Type of lymphocyte'''

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** T-cell.

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** B-cell.

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** NK-cell.

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* '''Time scale'''

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** Acute.

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** Chronic.

=====Prevalence=====

Bara

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