High Temperature Damage

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  • May result from excessive heat, liquids, flames, friction, lightning, electricity
  • Partial or full thickness burns (first, second and third degree burns)
  • Full thickness burns:
    • Total destruction of skin and adnexa
    • Has to be repaired by grafting
    • Life threatening
  • Partial thickness burns:
    • Some structures preserved -> regeneration may occur
    • Grossly:
      • Erythema (capillary dilation)
      • Oedema (increased permeability of capillaries)
      • Vesicles
    • Microscopically:
      • Coagulation necrosis of epidermis
      • Subepidermal vesiculation
      • Necrosis of adnexa
      • Degenerated subepidermal collagen
      • May involve large numbers of neutrophils if secondary ifection is present