Difference between revisions of "Kidney Endocrine Function - Anatomy & Physiology"
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The [[Urinary System Overview - Anatomy & Physiology#Upper Urinary Tract|Kidney]] synthesises and secretes various products, including [[Hormones - Anatomy & Physiology|hormones]] and enzymes which have a vital role within the body. | The [[Urinary System Overview - Anatomy & Physiology#Upper Urinary Tract|Kidney]] synthesises and secretes various products, including [[Hormones - Anatomy & Physiology|hormones]] and enzymes which have a vital role within the body. | ||
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| − | Kidneys are responsible for the production and release of two hormones [[Erythropoiesis#Regulation| | + | Kidneys are responsible for the production and release of two hormones; [[Erythropoiesis#Regulation|erythropoietin]] and [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology#Renin|renin]]. Both of these hormones are from the [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology#Juxtaglomerular Cells|juxtaglomerular cells]]. It is also responsible for the regulation of the [[Calcium #Active Vitamin D Synthesis |activation of vitamin D]]. |
==Renin== | ==Renin== | ||
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| − | + | A proteolytic enzyme synthesised in the kidney. Renin affects blood pressure indirectly and is part of the first stage of the [[Renin Angiotensin Aldosterone System| renin-angiotensin-aldosterone-system]]. Its effects are through its activation of this system by the conversion of angiotensinogen to angiotensin 1. | |
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==Erythropoietin== | ==Erythropoietin== | ||
| − | Erythropoietin is a glycoprotein hormone produced in the kidneys in adult life. | + | Erythropoietin is a glycoprotein hormone produced in the kidneys in adult life. Its function is beyond the scope of this section and more information can be found [[Erythropoiesis#Regulation|here]]. |
==Vitamin D== | ==Vitamin D== | ||
| − | The | + | The [[Calcium#Active Vitamin D Synthesis|activation of vitamin D]] is regulated by the kidneys under the influence of another hormone, [[Calcium#Parathyroid Hormone (PTH)|PTH]]. |
[[Category:Endocrine System - Anatomy & Physiology]][[Category:Kidney - Anatomy & Physiology]] | [[Category:Endocrine System - Anatomy & Physiology]][[Category:Kidney - Anatomy & Physiology]] | ||
| − | [[Category:To Do - | + | [[Category:To Do - AimeeHicks]] |
Revision as of 16:36, 7 January 2011
Overview
The Kidney synthesises and secretes various products, including hormones and enzymes which have a vital role within the body.
| Product | Action |
|---|---|
| Renin | This enzyme forms a vital part of the Renin-Angiotensin-Aldosterone System, a complex system of hormones and enzymes which act to raise blood pressure when stimulated by hypotension.
Renin is the enzyme required for the creation of the hormone angiotensin. |
| Erythropoietin | Erythropoeitin is the vital hormone for Erythropoeisis, the production of red blood cells. |
| Calcitriol | Also known as Active Vitamin D3, or 1-25-Dihydroxyvitamin D3, Calcitriol is vital for Calcium Homeostasis, and acts to raise plasma calcium levels. Within the kidney, vitamin D from dietary sources or the skin is 'activated' by hydroxylation. |
Kidneys are responsible for the production and release of two hormones; erythropoietin and renin. Both of these hormones are from the juxtaglomerular cells. It is also responsible for the regulation of the activation of vitamin D.
Renin
A proteolytic enzyme synthesised in the kidney. Renin affects blood pressure indirectly and is part of the first stage of the renin-angiotensin-aldosterone-system. Its effects are through its activation of this system by the conversion of angiotensinogen to angiotensin 1.
Erythropoietin
Erythropoietin is a glycoprotein hormone produced in the kidneys in adult life. Its function is beyond the scope of this section and more information can be found here.
Vitamin D
The activation of vitamin D is regulated by the kidneys under the influence of another hormone, PTH.