Difference between revisions of "Kidney Endocrine Function - Anatomy & Physiology"
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==Overview== | ==Overview== | ||
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The [[Calcium#Active Vitamin D Synthesis|activation of vitamin D]] is regulated by the kidneys under the influence of another hormone, [[Calcium#Parathyroid Hormone (PTH)|PTH]]. | The [[Calcium#Active Vitamin D Synthesis|activation of vitamin D]] is regulated by the kidneys under the influence of another hormone, [[Calcium#Parathyroid Hormone (PTH)|PTH]]. | ||
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[[Category:Endocrine System - Anatomy & Physiology]][[Category:Kidney - Anatomy & Physiology]] | [[Category:Endocrine System - Anatomy & Physiology]][[Category:Kidney - Anatomy & Physiology]] | ||
[[Category:A&P Done]] | [[Category:A&P Done]] | ||
Latest revision as of 13:37, 29 June 2012
Overview
The kidney synthesises and secretes various products, including hormones and enzymes which have a vital role within the body.
| Product | Action |
|---|---|
| Renin | This enzyme forms a vital part of theRenin-Angiotensin-Aldosterone System]], a complex system of hormones and enzymes which act to raise blood pressure when stimulated by hypotension.
Renin is the enzyme required for the creation of the hormone angiotensin. |
| Erythropoietin | Erythropoeitin is the vital hormone for erythropoeisis, the production of red blood cells. |
| Calcitriol | Also known as Active Vitamin D3, or 1-25-Dihydroxyvitamin D3, Calcitriol is vital for calcium homeostasis, and acts to raise plasma calcium levels. Within the kidney, vitamin D from dietary sources or the skin is 'activated' by hydroxylation. |
Renin
A proteolytic enzyme synthesised in the kidney. Renin affects blood pressure indirectly and is part of the first stage of the renin-angiotensin-aldosterone-system. Its effects are through its activation of this system by the conversion of angiotensinogen to angiotensin 1.
Erythropoietin
Erythropoietin is a glycoprotein hormone produced in the kidneys in adult life. Its function is beyond the scope of this section and more information can be found on regulatioon of erythropoiesis.
Vitamin D
The activation of vitamin D is regulated by the kidneys under the influence of another hormone, PTH.
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