Difference between revisions of "Liver Pigmentation"

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Revision as of 14:02, 26 September 2008


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()Map ALIMENTARY SYSTEM (Map)
LIVER



Congenital melanosis

  • in calves and lambs
  • black discoloration of small irregular portions of the liver


Haemosiderin

  • in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage
  • found within the Kuppfer cells
  • use Perls' stain

Lipofuscin

  • an insoluble golden brown pigment which occurs within hepatocytes
  • use Schmorl's stain - dark blue
  • increases with age - called the 'senility' pigment
  • it is commonly seen in hepatocytes near to the centrilobular vein in older cats
  • no clinical significance

Bile

  • especially prominent in obstructive jaundice
  • discolours the tissues green
  • intrahepatic bile canaliculi are distended with a greenish pigment - called bile plugs
  • larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called bile lakes
  • use Fouchet stain - green