Liver Flashcards - Pathology

Question	Answer		Article
Liver lesions are common because:	Liver is an area of high metabolic activity Receives toxic agents from the gut via the portal blood system Has an extensive vascular supply (prime site for metastatic disease)		Link to Article
In each type of jaundice, will bilirubinuria be detected? Haemolytic Obstructive Hepatocellular	Haemolytic NO - because most of bilirubin is unconjugated Obstructive YES - because conjugated bilirubin accumulates Hepatocellular NO - because bilirubin fails to conjugate due to liver cell damage NB - the kidney can only excrete the water soluble conjugate		Link to Article
In regard to secondary photosensitisation, what are two hepatotoxic plants?	Senecio jacobea (Ragwort) Lantana camara (Lantana) Lupinus angustifolius (Lupins) Blue-green algae		Link to Article
What are two causes of necrosis?	Severe metabolic disturbances Nutritional deficiencies Toxic substances Actions of micro-organisms		Link to Article
What can cause the liver to appear greenish-blue post mortem?	Bacteria degrade blood pigment to hydrogen sulfide		Link to Article
True or false? Cranial displacements of the liver are the most common.	False		Link to Article
What occurs during congestion?	The right side of the heart fails to function properly and blood will back up through the veins into the liver.		Link to Article
True or false? Congenital melanosis in calves and lambs appears as white discoloration of small irregular portions of the liver.	False		Link to Article
Hepatic lipidosis or fatty liver syndrome is associated with?	Dietary factors: obesity and starvation Increased demand for energy: pregnancy, lactation, and starvation in physiological states Diabetes mellitus, ketosis, and pregnancy toxaemia in pathological conditions Abnormal hepatocytic function: prevents fatty acids from forming complexes with proteins to form low density lipoproteins for secretion into the blood		Link to Article
What could be a non-pathological reason for a cow displaying fatty liver syndrome during necropsy?	It is possible to show fat infiltration of liver in cows which have not been eating for several days.		Link to Article
True or false? Equine hyperlipidemia or fat pony syndrome is similar to that in cats, as well as fatal within a week.	True		Link to Article
What causes Lysosomal storage disease and how does it manifest itself?	Due to an inherited deficiency of lysosomal enzymes Manifest themselves as neurological disease		Link to Article
Herpes virus infections include:	Equine Viral Rhinopneumonitis Infectious Bovine Rhinotracheitis Feline Viral Rhinopneumonitis Aujesky's disease in pigs		Link to Article
You are examining a cow's liver at necropsy. You notice the liver has several small areas of necrosis. Is this more likely to be Black Disease or Red Water Disease?	Black Disease		Link to Article
What are the two main types of hepatitis in cats?	Cholangitis Lymphocytic portal hepatitis		Link to Article
True or false? Use of carbon tetrachloride as an anthelmintic and phosphorous as a rodenticide has never been proven to produce liver necrosis.	False		Link to Article
Pyrrolizidine alkaloids have an anti-mitotic effect whilst allowing continued synthesis within the cell and its nucleus. This causes a marked increase in the size of parenchymal cells, a phenomenon termed -	(Hepato)megalocytosis		Link to Article
Haemangiosarcoma can be primary in the liver, what are other predilection sites?	Spleen Right auricle of the heart		Link to Article
True or false? Chronic lymphocytic cholangitis generally afflicts only very young cats.	False		Link to Article
What are two causes of cholangitis of the liver?	Ascending infections from the intestine Associated with organisms excreted via the bile		Link to Article