Difference between revisions of "Viral skin infections - Pathology"
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| + | |backcolour = FFCCCC | ||
| + | |linkpage =Integumentary System - Pathology | ||
| + | |linktext =Integumentary System | ||
| + | |maplink = Integumentary System (Content Map) - Pathology | ||
| + | |pagetype =Pathology | ||
| + | |sublink1 = Skin Infectious - Pathology | ||
| + | |subtext1 = SKIN INFECTIOUS | ||
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| + | <br> | ||
| + | ===[[Herpesviridae|Herpesviruses]]=== | ||
| + | [[Herpesvirus Skin Infections]] | ||
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| + | ===[[Poxviruses]]=== | ||
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| + | *Lesion development: | ||
| + | **Due to viral invasion of epithelium | ||
| + | **Vascular injury -> ischaemic necrosis | ||
| + | **Stimulation of host DNA -> hyperplastic nodules | ||
| + | *Cutaneous lesions: | ||
| + | **[[Skin Glossary - Pathology|Macule]] -> [[Skin Glossary - Pathology|papule]] -> [[Skin Glossary - Pathology|vesicle]] -> umbilicated [[Skin Glossary - Pathology|pustule]] -> [[Skin Glossary - Pathology|crust]] -> [[Skin Glossary - Pathology|scar]] | ||
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| + | ====Contagious ecthyma==== | ||
| + | [[Image: Contagious ecthyma.jpg|100px|thumb|right|<small><center>Contagious ecthyma (Courtesy of Bristol BioMed Image Archive)</center></small>]] | ||
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| + | *Also called '''contagious pustular dermatitis, orf, sore mouth''' | ||
| + | *Caused by a [[Poxviridae|parapox virus]] | ||
| + | *Affects mainly young sheep, less commonly cattle, humans, dogs | ||
| + | *Starts in abrasions around mouth commisures and spreads to [[Lips - Anatomy & Physiology|lips]], oral mucosa, eyelids and feet | ||
| + | *May also transfer to teats of the mother of an affected lamb | ||
| + | *Lesions typical of poxvirus but very brief vesicle stage | ||
| + | *Most obvious is the proliferative pustular stage | ||
| + | |||
| + | ===Other viruses=== | ||
| + | *Cutaneous lesion are seen with: | ||
| + | **[[Picornaviridae]] | ||
| + | ***[[Foot and Mouth Disease|Foot-and-mouth disease]] | ||
| + | ***[[Swine Vesicular Disease|Swine vesicular disease]] | ||
| + | **[[Rhabdoviridae]] | ||
| + | ***Vesicular stomatitis | ||
| + | **[[Caliciviridae]] | ||
| + | ***Vesicular exanthema | ||
| + | **[[Retroviridae]] | ||
| + | ***'''Feline leukemia virus''' | ||
| + | ****Cutaneous horns on foot pads | ||
| + | ****Epidermal and follicular epithelial hyperplasia, epidermal giant cells, dyskeratosis, necrosis, ulceration | ||
| + | ***'''Feline immunodeficiency virus''' | ||
Revision as of 10:59, 30 June 2010
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Herpesviruses
Poxviruses
- Lesion development:
- Due to viral invasion of epithelium
- Vascular injury -> ischaemic necrosis
- Stimulation of host DNA -> hyperplastic nodules
- Cutaneous lesions:
Contagious ecthyma
- Also called contagious pustular dermatitis, orf, sore mouth
- Caused by a parapox virus
- Affects mainly young sheep, less commonly cattle, humans, dogs
- Starts in abrasions around mouth commisures and spreads to lips, oral mucosa, eyelids and feet
- May also transfer to teats of the mother of an affected lamb
- Lesions typical of poxvirus but very brief vesicle stage
- Most obvious is the proliferative pustular stage
Other viruses
- Cutaneous lesion are seen with:
- Picornaviridae
- Rhabdoviridae
- Vesicular stomatitis
- Caliciviridae
- Vesicular exanthema
- Retroviridae
- Feline leukemia virus
- Cutaneous horns on foot pads
- Epidermal and follicular epithelial hyperplasia, epidermal giant cells, dyskeratosis, necrosis, ulceration
- Feline immunodeficiency virus
- Feline leukemia virus