Difference between revisions of "Pasteurella multocida"

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*Large grey colonies on blood agar
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*Not haemolytic
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==Introduction==
*Do not grow on MacConkey
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''P.multocida'' is a very small, non-motile, gram-negative, ovoid, coccoid or short rod. It is aerobic and facultatively anaerobic species of the [[:Category:Pasteurella and Mannheimia species|''Pasteurella'']] genus. It forms large, grey colonies on blood agar and is not haemolytic. It does not grow on MacConkey. It has five capsular serotypes, A,B,D,E and F and can be a primary and secondary pathogen. It is responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Enzootic Pneumonia - Calves|Enzootic pneumonia of calves]] and pigs. It can cause [[Haemorrhagic_Disease_Pathophysiology#Vascular_Fragility|vascular fragility]], leading to haemorrhagic disease. It is also involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites. It causes [[Pasteurellosis - Rabbit|respiratory disease in rabbits]].
*Five capsular serotypes, A,B,D,E and F
 
*Primary and secondary pathogen
 
*Responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]] and pigs
 
* Can cause vascular fragility, leading to [[Haemostasis - Pathology#Haemorrhagic Disease Due To Vascular Fragility|haemorrhagic disease]]
 
*Involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites
 
  
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==Type A==
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Type A is a commensal in the upper respiratory tract of animals in the UK. It is a primary pathogen in avian cholera - a septicaemia in chickens and turkeys. It is a secondary pathogen commonly responsible for dog and cat bite wound infections in humans and animals. It is also involved in feline pyothorax and cellulitis.
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Some strains are involved in [[Atrophic Rhinitis]] of pigs, and produce osteolytic toxin. It is also involved in [[Snuffles|snuffles]] in rabbits, a mucopurulent rhinosinusitis and can cause pneumonia and mastitis in sheep. In cattle it is associated with [[Pneumonic Pasteurellosis|pneumonic pasteurellosis]], as well as enzootic pneumonia in calves.
  
*Typa A
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==Type B==
**Commensal in upper respiratory tract of animals in UK
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Type B causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia.
**Primary pathogen in avian cholera - a septicaemia in chickens and turkeys
 
**Secondary pathogen commomly repsonsible for dog and cat bite wound infections in humans and animals
 
**Feline pyothorax and [[Muscles Inflammatory - Pathology#Abscesses|cellulitis]]
 
**Some strains involved in [[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis of pigs]], and produce osteolytic toxin
 
**Involved in [[Respiratory Bacterial Infections - Pathology#In Rabbits|'Snuffles' in rabbits]], a mucopurulent rhinosinitis
 
**Can cause pneumonia and mastitis in sheep
 
**Associated with [[Respiratory Bacterial Infections - Pathology#Pneumonic pasteurellosis|pneumonic pasteurellosis]] in cattle, as well as enzootic pneumonia in calves
 
  
*Type B
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==Type D==
**Causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia
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Type D is a primary and secondary pathogen. It causes [[Atrophic Rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs. ''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]'' and produce an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates.
  
*Type D
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==Type E==
**Primary and secondary pathogen
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Type E causes African Bovine Haemorrhagic Septicaemia.
**Causes [[Respiratory Bacterial Infections - Pathology#In Pigs|atrophic rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs
 
**Pneumonia in pigs
 
**''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]''
 
**Produces an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates
 
  
*Type E
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**Causes African Bovine Haemorrhagic Septicaemia[[Category:Pasteurella and Mannheimia species]]
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{{Learning
[[Category:Cattle]][[Category:Pig]][[Category:Poultry]][[Category:Rabbit]]
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|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Pasteurella+multocida%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=50&y=9 ''Pasteurella multocida'' publications since 2000]
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}}
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{{review}}
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{{OpenPages}}
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[[Category:Pasteurella and Mannheimia species]].
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[[Category:Expert_Review - Bacteria]]

Latest revision as of 14:14, 20 July 2012


Introduction

P.multocida is a very small, non-motile, gram-negative, ovoid, coccoid or short rod. It is aerobic and facultatively anaerobic species of the Pasteurella genus. It forms large, grey colonies on blood agar and is not haemolytic. It does not grow on MacConkey. It has five capsular serotypes, A,B,D,E and F and can be a primary and secondary pathogen. It is responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during Enzootic pneumonia of calves and pigs. It can cause vascular fragility, leading to haemorrhagic disease. It is also involved in subcutaneous abscesses due to cat bites. It causes respiratory disease in rabbits.

Type A

Type A is a commensal in the upper respiratory tract of animals in the UK. It is a primary pathogen in avian cholera - a septicaemia in chickens and turkeys. It is a secondary pathogen commonly responsible for dog and cat bite wound infections in humans and animals. It is also involved in feline pyothorax and cellulitis. Some strains are involved in Atrophic Rhinitis of pigs, and produce osteolytic toxin. It is also involved in snuffles in rabbits, a mucopurulent rhinosinusitis and can cause pneumonia and mastitis in sheep. In cattle it is associated with pneumonic pasteurellosis, as well as enzootic pneumonia in calves.

Type B

Type B causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia.

Type D

Type D is a primary and secondary pathogen. It causes Atrophic Rhinitis along with Bordetella bronchiseptica in pigs. Pasteurella multocida adhere to epithelium damaged by Bordetella bronchiseptica and produce an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates.

Type E

Type E causes African Bovine Haemorrhagic Septicaemia.



Pasteurella multocida Learning Resources
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