Difference between revisions of "Sjorgren’s-like syndrome"

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*Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Oral Cavity - Salivary Glands - Anatomy & Physiology|salivary glands]].
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*Both those terms refer to cessation of production of tear or [[Oral Cavity - Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively.
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== Introduction ==
*May be primary autoimmune or part of another autoimmune condition.
 
*Causes of xerostomia:
 
**Dysautonomia
 
**Infectious sialadenitis
 
**Neoplasia
 
**Salivary amyloidosis
 
**Head and neck radiation
 
**Drugs
 
**AutoI disease.
 
  
'''Tagging-PG'''
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This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.
  
[[Category:Salivary Glands - Pathology]]
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Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.
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== Clinical Signs ==
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Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[Periodontal Disease|gingivitis]] and [[glossitis]] are all possible clinical signs.
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== Diagnosis ==
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Diagnosis by elimination of all other causes of these clinical signs.
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== Treatment ==
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None
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Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.
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== Prognosis ==
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Guarded to Poor
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{{Learning
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|Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis60223.asp Sjogren's-like syndrome]
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}}
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== References ==
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Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial
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Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.
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Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins.
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{{review}}
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{{OpenPages}}
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[[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]]

Latest revision as of 17:55, 25 June 2016


Introduction

This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of salivary glands. Both those terms refer to cessation of production of tear or saliva respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.

Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.


Clinical Signs

Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, stomatitis, gingivitis and glossitis are all possible clinical signs.


Diagnosis

Diagnosis by elimination of all other causes of these clinical signs.


Treatment

None

Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.


Prognosis

Guarded to Poor



Sjorgren’s-like syndrome Learning Resources
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References

Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial

Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.

Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins.




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