Difference between revisions of "Cryptococcosis"
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m (Text replace - "[[Urinary System - Anatomy & Physiology" to "[[Urinary System Overview - Anatomy & Physiology") |
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*Over 19 species | *Over 19 species | ||
− | **'' | + | **''C. neoformans'' only major pathogen |
*Worldwide | *Worldwide | ||
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**Latex agglutination for [[Adaptive Immune System - Overview#Actions of the Adaptive Immune System|antigen]], complement fixation, ELISA and IFAT can be used | **Latex agglutination for [[Adaptive Immune System - Overview#Actions of the Adaptive Immune System|antigen]], complement fixation, ELISA and IFAT can be used | ||
− | + | ==Test yourself with the Yeast-like Fungi Flashcards== | |
− | + | ||
− | + | [[Yeast-like_Fungi_-_Flashcards#Cryptococcosis|Cryptococcosis Flashcards]] | |
− | + | ||
+ | ==Links== | ||
+ | |||
+ | ===''[[Cryptococcus neoformans]]''=== | ||
[[Category:Respiratory Fungal Infections]] | [[Category:Respiratory Fungal Infections]] |
Revision as of 16:14, 10 December 2010
- Over 19 species
- C. neoformans only major pathogen
- Worldwide
- Occurs in high concentrations in pigeon droppings (high creatinine concentration)
- The pigeon is not infected
- C. neoformis colonise the droppings after they have been excreted
- Also found in fruit, milk and soil
- Exogenous, inhaled infection which is generally sporadic (non-contageous)
- Can also be absorbed via skin penetration and ingestion
- May be a primary pathogen or opportunistic
- Targets the respiratory system
- Including the paranasal sinuses
- Also can be systemic, cutaneous, visceral, skeletal or ocular
- Causes sporadic mastitis in cattle
- Can spread within the herd
- Affects the CNS of dogs and cats
- Causes cryptococcal meningitis in humans
- Also affects dolphins, foxes, ferrets, monkeys, birds, cheetahs and guinea-pigs
- Large yeast with capsule seen using India ink stain
- Stains with PAS (Periodic acis Schiff)
- Gram positive
- Grows on blood agar and Sabouraud's Dextrose agar forming white, granular colonies which become slimy, mucoid and turn creamy/brown within a week
- Species identified by carbohydrate assimilation tests
- Antigen and antibody should be tested for as antibody formed by the body is soon overwhelmed and neutralised by abundent polysaccharide antigen from the capsule in active, systemic infections
- Latex agglutination for antigen, complement fixation, ELISA and IFAT can be used