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==Introduction==

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''P.multocida'' is a very small, non-motile, gram-negative, ovoid, coccoid or short rod. It is aerobic and facultatively anaerobic species of the [[:Category:Pasteurella and Mannheimia species|''Pasteurella'']] genus. It forms large, grey colonies on blood agar and is not haemolytic. It does not grow on MacConkey. It has five capsular serotypes, A,B,D,E and F and can be a primary and secondary pathogen. It is responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Enzootic Pneumonia - Calves|Enzootic pneumonia of calves]] and pigs. It can cause [[Haemorrhagic_Disease_Pathophysiology#Vascular_Fragility|vascular fragility]], leading to haemorrhagic disease. It is also involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites. It causes [[Pasteurellosis - Rabbit|respiratory disease in rabbits]].

| ''P.multocida''

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''P.multocida'' is a species of the [[:Category:Pasteurella and Mannheimia species|''Pasteurella'']] genus. It forms large, grey colonies on blood agar and is not haemolytic. It does not grow on MacConkey. It has five capsular serotypes, A,B,D,E and F and can be a primary and secondary pathogen. It is responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]] and pigs. It can cause vascular fragility, leading to [[Haemostasis - Pathology#Haemorrhagic Disease Due To Vascular Fragility|haemorrhagic disease]]. It is also involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites.

 

==Type A==

==Type A==

Type A is a commensal in the upper respiratory tract of animals in the UK. It is a primary pathogen in avian cholera - a septicaemia in chickens and turkeys. It is a secondary pathogen commomly repsonsible for dog and cat bite wound infections in humans and animals. It is also involved in feline pyothorax and [[Muscles Inflammatory - Pathology#Abscesses|cellulitis]].  

Type A is a commensal in the upper respiratory tract of animals in the UK. It is a primary pathogen in avian cholera - a septicaemia in chickens and turkeys. It is a secondary pathogen commonly responsible for dog and cat bite wound infections in humans and animals. It is also involved in feline pyothorax and cellulitis.  

Some strains are involved in [[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis of pigs]], and produce osteolytic toxin. It is also involved in [[Snuffles]], a mucopurulent rhinosinitis  and can cause pneumonia and mastitis in sheep. In cattle it is associated with [[Respiratory Bacterial Infections - Pathology#Pneumonic pasteurellosis|pneumonic pasteurellosis]], as well as enzootic pneumonia in calves.

Some strains are involved in [[Atrophic Rhinitis]] of pigs, and produce osteolytic toxin. It is also involved in [[Snuffles|snuffles]] in rabbits, a mucopurulent rhinosinusitis and can cause pneumonia and mastitis in sheep. In cattle it is associated with [[Pneumonic Pasteurellosis|pneumonic pasteurellosis]], as well as enzootic pneumonia in calves.

==Type B==

==Type B==

==Type D==

==Type D==

Type D is a primary and secondary pathogen. It causes [[Respiratory Bacterial Infections - Pathology#In Pigs|atrophic rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs. ''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]'' and produce an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates.

Type D is a primary and secondary pathogen. It causes [[Atrophic Rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs. ''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]'' and produce an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates.

==Type E==

==Type E==

Type E causes African Bovine Haemorrhagic Septicaemia[[Category:Pasteurella and Mannheimia species]].

Type E causes African Bovine Haemorrhagic Septicaemia.

 

 

|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Pasteurella+multocida%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=50&y=9 ''Pasteurella multocida'' publications since 2000]

 

 

[[Category:To_Do_-_AimeeHicks]]

[[Category:Pasteurella and Mannheimia species]].

[[Category:Expert_Review - Bacteria]]