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===Aetiology===
===Aetiology===
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreas Degenerative - Pathology#Acute pancreatic necrosis|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
*Causes [[DM|Diabetes mellitus]] (DM)
*Causes [[DM|Diabetes mellitus]] (DM)
**'''Sclerosis''' of the islets is sometimes observed in dogs with [[DM|DM]] without pancreatic necrosis but also in dogs without DM
**'''Sclerosis''' of the islets is sometimes observed in dogs with [[DM|DM]] without pancreatic necrosis but also in dogs without DM
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'''For degeneration of exocrine tissue''' see [[Pancreas Degenerative - Pathology|'degenerative disease of exocrine pancreas in Alimentary section']]
'''For degeneration of exocrine tissue''' see [[:Category:Pancreas - Degenerative Pathology|'degenerative disease of exocrine pancreas in Alimentary section']]
==Neoplasia==
==Neoplasia==
[[Image:Islet cell tumour.jpg|right|thumb|100px|<small><center>Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
[[Image:Islet cell tumour.jpg|right|thumb|100px|<small><center>Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]