Difference between revisions of "Lymphopenia"

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==Description==
 
==Description==
 
Lymphopenia is a reduction in the numbers of lymphocytes in the blood.  This phenomenon is most commonly associated with stress (as part of the '''stress leucogram''') or with viral infection.  Causes include:
 
Lymphopenia is a reduction in the numbers of lymphocytes in the blood.  This phenomenon is most commonly associated with stress (as part of the '''stress leucogram''') or with viral infection.  Causes include:
*Stress leucogram, characterised by '''[[Neutrophilia|neutrophilia]]''', '''[[Monocytosis|monocytosis]]''', '''[[Eosinopenia|eosinopenia]]''' and '''[[Lymphopenia|lymphopenia]]'''.  A similar pattern may occur with hyperadrenocorticism (Cushing’s disease) or exogenous corticosteroid therapy as these hormones selectively suppress lymphocytic activity and the inflammatory response in general.   
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*[[Stress leucogram]], characterised by '''[[Neutrophilia|neutrophilia]]''', '''[[Monocytosis|monocytosis]]''', '''[[Eosinopenia|eosinopenia]]''' and '''[[Lymphopenia|lymphopenia]]'''.  A similar pattern may occur with hyperadrenocorticism (Cushing’s disease) or exogenous corticosteroid therapy as these hormones selectively suppress lymphocytic activity and the inflammatory response in general.   
 
*Viral infection with [[Canine Distemper Virus|canine distemper]], [[Infectious canine hepatitis]], [[Feline infectious enteritis|feline infectious enteritis]] or [[Bovine Viral Diarrhoea|bovine viral diarrhoea]] (BVD)
 
*Viral infection with [[Canine Distemper Virus|canine distemper]], [[Infectious canine hepatitis]], [[Feline infectious enteritis|feline infectious enteritis]] or [[Bovine Viral Diarrhoea|bovine viral diarrhoea]] (BVD)
 
*Bone marrow suppression caused by '''chemotherapy''' or '''radiotherapy'''.  Since neutrophils have a much shorter circulating half life, they are the first cell line to fall with any insult to the bone marrow but lymphopenia may occur as part of a more severe pancytopenia.
 
*Bone marrow suppression caused by '''chemotherapy''' or '''radiotherapy'''.  Since neutrophils have a much shorter circulating half life, they are the first cell line to fall with any insult to the bone marrow but lymphopenia may occur as part of a more severe pancytopenia.

Revision as of 14:07, 11 February 2011


Description

Lymphopenia is a reduction in the numbers of lymphocytes in the blood. This phenomenon is most commonly associated with stress (as part of the stress leucogram) or with viral infection. Causes include:

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