Mycoplasma hyopneumoniae
| Mycoplasma hyopneumoniae | |
|---|---|
| Phylum | Firmicutes |
| Class | Mollicutes |
| Order | Mycoplasmatales |
| Family | Mycoplasmataceae |
| Genus | Mycoplasma |
| Species | M.hyopneumoniae |
Introduction
Mycoplasma hyopneumoniae is a very small, gram positive bacterial pathogen. It is round in shape and stores its DNA in a nucleolus and in fibrillar cytoplasmic material.
Culture of M. hyopneumoniae is difficult and time-consuming and requires specialised media. It grows slowly, requires 5-10% carbon dioxide and produces an acid colour shift. Because of the time taken, contamination is very common, especially with other Mycoplasmas.
Pathogenesis
M. hyopneumoniae adheres to the cilia of the respiratory tract[1], causing ciliostasis, clumping and loss.[2] This is followed by loss of epithelial cells and goblet cells. [3] This reduces the efficacy of mucociliary clearance and allows the colonisation of the secondary pathogens that are usually involved in Enzootic Pneumonia.
M. hyopneumoniae also alters many other aspects of the host’s immune system, including B and T lymphocyte driven immunity, alveolar macrophages and the production of pro-inflammatory cytokines.
Mononuclear infiltration of peribronchiolar and perivascular areas is the basis of pneumonic lesions and often causes the formation of lymphoid nodules when disease is chronic, as it often is.
Pathogenicity and severity of disease are stipulated by the presence and interaction of M. hyopneumoniae with other pathogens.
Diseases
M. hyopneumoniae causes enzootic pneumonia in pigs.
| Mycoplasma hyopneumoniae Learning Resources | |
|---|---|
 Test your knowledge using flashcard type questions |
M. hyopneumoniae Flashcards |
 Search for recent publications via CAB Abstract (CABI log in required) |
Mycoplasma hyopneumoniae publications |
References
- ↑ Zielinski, G. C., Ross, R. F (1993) Adherence of Mycoplasma hyopneumoniae to porcine ciliated respiratory tract cells. American J Vet Research, 54(8):1262-1269; 27
- ↑ Debey, M. C., Ross, R. F (1994) Ciliostasis and loss of cilia induced by Mycoplasma hyopneumoniae in porcine tracheal organ cultures. Infection and Immunity, 62(12):5312-5318; 33
- ↑ Debey, M. C., Jacobson, C. D., Ross, R. F (1992) Histochemical and morphologic changes of porcine airway epithelial cells in response to infection with Mycoplasma hyopneumoniae. American Journal of Veterinary Research, 53(9):1705-1710; 28
|
This article was originally sourced from The Animal Health & Production Compendium (AHPC) published online by CABI during the OVAL Project. The datasheet was accessed on 25 June 2011. |
 |
This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
Error in widget FBRecommend: unable to write file /var/www/wikivet.net/extensions/Widgets/compiled_templates/wrt6767a7ee964953_60602201 Error in widget google+: unable to write file /var/www/wikivet.net/extensions/Widgets/compiled_templates/wrt6767a7ee9bbef4_63693664 Error in widget TwitterTweet: unable to write file /var/www/wikivet.net/extensions/Widgets/compiled_templates/wrt6767a7eea08737_18865211
|
| WikiVet® Introduction - Help WikiVet - Report a Problem |