Difference between revisions of "Lymphopenia"
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Lymphopenia is a reduction in the numbers of lymphocytes in the blood. This phenomenon is most commonly associated with stress (as part of the '''stress leucogram''') or with viral infection. Causes include: | Lymphopenia is a reduction in the numbers of lymphocytes in the blood. This phenomenon is most commonly associated with stress (as part of the '''stress leucogram''') or with viral infection. Causes include: | ||
*[[Stress Leucogram|Stress leucogram]], characterised by '''[[Neutrophilia|neutrophilia]]''', '''[[Monocytosis|monocytosis]]''', '''[[Eosinopenia|eosinopenia]]''' and '''[[Lymphopenia|lymphopenia]]'''. A similar pattern may occur with hyperadrenocorticism (Cushing’s disease) or exogenous corticosteroid therapy as these hormones selectively suppress lymphocytic activity and the inflammatory response in general. | *[[Stress Leucogram|Stress leucogram]], characterised by '''[[Neutrophilia|neutrophilia]]''', '''[[Monocytosis|monocytosis]]''', '''[[Eosinopenia|eosinopenia]]''' and '''[[Lymphopenia|lymphopenia]]'''. A similar pattern may occur with hyperadrenocorticism (Cushing’s disease) or exogenous corticosteroid therapy as these hormones selectively suppress lymphocytic activity and the inflammatory response in general. | ||
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*Leakage of lymphatic fluid may result in loss of lymphocytes, as occurs with '''[[Lymphangiectasia|lymphangiectasia]]''' or '''[[Chylous Effusion|chylothorax]]'''. | *Leakage of lymphatic fluid may result in loss of lymphocytes, as occurs with '''[[Lymphangiectasia|lymphangiectasia]]''' or '''[[Chylous Effusion|chylothorax]]'''. | ||
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| − | + | |literature search = [http://www.cabdirect.org/search.html?it=any&q2=lymphopaenia&q1=lymphopenia&calendarInput=yyyy-mm-dd&occuring1=title&show=all&rowId=1&rowId=2&rowId=3&options1=AND&options2=OR&options3=AND&occuring3=freetext&occuring2=title&publishedend=yyyy&la=any&publishedstart=yyyy&fq=sc%3A%22ve%22&y=6&x=40 Publications with 'lymphopenia' in their title] | |
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| − | [[Category:Haematology Changes]][[Category:Expert Review]] | + | [[Category:Haematology Changes]][[Category:Expert Review]][[Category:Bullet Points]] |
Revision as of 20:24, 11 July 2012
Introduction
Lymphopenia is a reduction in the numbers of lymphocytes in the blood. This phenomenon is most commonly associated with stress (as part of the stress leucogram) or with viral infection. Causes include:
- Stress leucogram, characterised by neutrophilia, monocytosis, eosinopenia and lymphopenia. A similar pattern may occur with hyperadrenocorticism (Cushing’s disease) or exogenous corticosteroid therapy as these hormones selectively suppress lymphocytic activity and the inflammatory response in general.
- Viral infection with canine distemper, Infectious canine hepatitis, feline infectious enteritis or bovine viral diarrhoea (BVD)
- Bone marrow suppression caused by chemotherapy or radiotherapy. Since neutrophils have a much shorter circulating half life, they are the first cell line to fall with any insult to the bone marrow but lymphopenia may occur as part of a more severe pancytopenia.
- Inherited or acquired immunodeficiency syndromes, including SCID (Severe Combined Immunodeficiency Syndrome) in Arab foals and feline immunodeficiency virus infection.
- Leakage of lymphatic fluid may result in loss of lymphocytes, as occurs with lymphangiectasia or chylothorax.
| Lymphopenia Learning Resources | |
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Publications with 'lymphopenia' in their title |
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