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| | ==Introduction== | | ==Introduction== |
| | [[File:Fibrous epulis.JPG|thumb|200px|right|Fibrous epulis]] | | [[File:Fibrous epulis.JPG|thumb|200px|right|Fibrous epulis]] |
| − | Peripheral odontogenic fibroma is a benign tumour that arises from the [[Enamel Organ#Periodontal Ligament|periodontal ligament]]. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization. | + | Peripheral odontogenic fibroma is a benign tumour that arises from the [[Tooth - Anatomy & Physiology#Periodontal Ligament|periodontal ligament]]. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization. |
| | They present as firm, smooth swellings of the [[Gingiva|gingiva]] and are normally indistinguishable from [[Gingival Hyperplasia|gingival hyperplasia]]. | | They present as firm, smooth swellings of the [[Gingiva|gingiva]] and are normally indistinguishable from [[Gingival Hyperplasia|gingival hyperplasia]]. |
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| | ==Diagnostic Imaging== | | ==Diagnostic Imaging== |
| − | Radiographs are required to differentiate this benign neoplasm from malignant or locally aggressive lesions. Skull radiographs will evaluate the oral lesion itself and thoracic radiography to evaluate for metastasies (if a malignancy is a diagnostic possibility). Radiographs typically show a soft tissue opacity in the the gingiva region with varying degrees of mineralization. Bone involvement is not a feature of this neoplasm and hence is not to be confused with [[Acanthomatous Ameloblastoma|Acanthomatous Ameloblastoma]] which often invades bone. | + | Radiographs are required to differentiate this benign neoplasm from malignant or locally aggressive lesions. Intra-oral radiographs will evaluate the oral lesion itself and thoracic radiography to evaluate for metastasies (if a malignancy is a diagnostic possibility). Radiographs typically show a soft tissue opacity in the the gingiva region with varying degrees of mineralization. Bone involvement is not a feature of this neoplasm and hence is not to be confused with [[Acanthomatous Ameloblastoma|Acanthomatous Ameloblastoma]] which often invades bone. |
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| | Radiography cannot be used to differentiate a peripheral odontogenic fibroma from a hyperplastic gingival lesion. | | Radiography cannot be used to differentiate a peripheral odontogenic fibroma from a hyperplastic gingival lesion. |
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| | ==Pathology== | | ==Pathology== |
| | [[Image:epulis.gif|right|thumb|200px|<small><center>Canine Epulis(Courtesy of Alun Williams (RVC))</center></small>]] | | [[Image:epulis.gif|right|thumb|200px|<small><center>Canine Epulis(Courtesy of Alun Williams (RVC))</center></small>]] |
| − | Proliferation of fibrous tissue with a variety of osteoid, [[Enamel Organ#Cementum|cementum]] or [[Enamel Organ#Dentine|dentine]] like material. Isolated strands or islands of odontogenic epithelium are always present (ie: suggesting induction of connective tissue by the epithelial cells). | + | Proliferation of fibrous tissue with a variety of osteoid, [[Tooth - Anatomy & Physiology#Cementum|cementum]] or [[Tooth - Anatomy & Physiology#Dentine|dentine]] like material. Isolated strands or islands of odontogenic epithelium are always present (ie: suggesting induction of connective tissue by the epithelial cells). |
| | The stroma contains neoplastic fibroblasts, with varying cellularity and the overlying epitheluim is normal. | | The stroma contains neoplastic fibroblasts, with varying cellularity and the overlying epitheluim is normal. |
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| | {{Learning | | {{Learning |
| | |literature search = [http://www.cabdirect.org/search.html?q=title%3A%28%22Peripheral+Odontogenic+Fibroma%22%29+OR+%28title%3A%28epulis%29+AND+%28title%3A%28fibromatous%29+OR+title%3A%28ossifying%29%29%29 Peripheral Odontogenic Fibroma publications] | | |literature search = [http://www.cabdirect.org/search.html?q=title%3A%28%22Peripheral+Odontogenic+Fibroma%22%29+OR+%28title%3A%28epulis%29+AND+%28title%3A%28fibromatous%29+OR+title%3A%28ossifying%29%29%29 Peripheral Odontogenic Fibroma publications] |
| | + | |Vetstream = [https://www.vetstream.com/felis/Content/Disease/dis60094.asp Odontoclastic tooth resorption] |
| | }} | | }} |
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