Respiratory Bacterial Infections - Pathology

()Map CARDIORESPIRATORY SYSTEM (Map) RESPIRATORY SYSTEM INFLAMMATION

In general

• Main clinical expression is as secondary invaders of previously damaged lung tissue due to viral or parasitic involvement or environmental stress
• Some are initial pathogens in their own right while others can damage the tract allowing invasion by more pathogenic types

In Dogs

Infectious Canine Tracheitis

In Cattle

Necrotic Laryngitis

Cillia-associated Respiratory Bacillus

In Sheep

CAR bacillus

• As in cattle

In Pigs

Necrotic laryngitis in pigs

• As in cattle
• Caused by infection with Fusobacterium necrophorum

Pasteurellosis in pigs

• Pasteurella multocida can cause a severe acute fibrinous bronchopneumonia in pigs
• The most significant disease here is that caused by P. multocida secondary to underlying mycoplasma pneumonia, see above enzootic pneumonia of pigs
  • This results in chronic suppurative bronchopneumonia with abscessation and pleuritis
• If there is considerable pleural involvement, it may be indistinguishable from lesions caused by Haemophilus pleuropneumonia (below)
• Also isolated from cases of meningitis and septicaemia in piglets

Contagious porcine pleuropneumonia

• Caused by Haemophilus (Actinobacillus) pleuropneumonia
• Seen mainly between 6wks-6mths of age but will affect any age
• Highly pathogenic strains are capable of initiating disease on their own with high mortality in young pigs
• A fibrinonecrotic bronchopneumonia with pleurisy
• Foci of haemorrhagic consolidation or necrosis, mainly around major bronchi, tend to sequestrate
• Tending to spread throughout all lung lobes: therefore a cranioventral distribution may not be particularly evident

Glasser's disease

• Caused by Haemophilus parasuis
• May cause suppurative bronchopneumonia and pleuritis (as part of polyserositis)
• Stress of mixing, weaning and adverse environmental conditions are predisposing to the disease

Streptococcal pneumonia

• Caused by Streptococcus suis type II

Tuberculosis in pigs

• Pigs are susceptible to the Mycobacterium spp. causing tuberculosis in cattle
• Rarely extends to lungs after haematogenous spread from ingested bacteria causing tubercles with various degrees of calcification, encapsulation and caseation

In Rabbits

Snuffles

• Caused by Pasteurella multocida, less commonly and/or Bordetella bronchiseptica
• Clinical signs (nasal discharge, sneezing) result from an acute to chronic rhinitis

CAR bacillus

• As in cattle